(qRT-PCR) was used to detect the expression levels of the miR-183/182/96 cluster in 41 breast cancer tissues and adjacent normal tissues (control tissues) and also in different mammary cell lines.hybridization (ISH) of the miR-183/182/96 cluster on 131 tissue microarrays (TMAs) was used...
In situ hybridization (ISH) of the miR-183/182/96 cluster on 131 tissue microarrays (TMAs) was used to statistically analyze its prognostic role. The miR-183/182/96 cluster levels were significantly higher in breast cancer tissues than in control tissues. The miR-183/182/96 cluster was ...
Bulk RNA-seq and ATAC-seq analysis revealed the averaged gene expression level or chromatin accessibility on a population of cells in tissue samples, revealing two gene sets involved in the diterpenoid biosynthesis in root and shoot. However, the cell heterogeneity was not distinguished in bulked ti...
and increased fatigue was associated with decreased arachidonic acid [24] in women with breast cancer receiving chemotherapy. Targeted metabolomics analysis further indicated moderate-to-strong correlations between changes in pain and tryptophan, as well as between changes in depressive...
In all cases, we normalize the data using Seurat [14] before passing it to SpatialCPie. Human developmental heart The tissue section is taken from a 5-week-old heart with well-defined anatomical regions (Fig. 2b). Fig. 2 The human developmental heart. a Array plots. b H&E stain of...
Recently, with the advent of spatial omics and in a similar vein as the work presented here, analogous visualizations have also successfully been applied to tissue maps [9]. Implementation The user interface of SpatialCPie is implemented in Shiny [10]. The interface consists of two main ...
Background: Dysregulated cellular metabolism is a hallmark of breast cancer, and targeting it has promising implications for improving care and patient outcomes. Specifically, heterogeneity in tumor metabolism is thought to play a role i... DJ Cook,J Whitman,N Liadis,... - 《Cancer Research》 ...
breast cancer. There's no time for cluster headaches but that doesn't stop them. I wish it would just stop. I've reached that point where you feel that you can't take it any more-but we do. Sorry to sound so negative right now but I have no meds except ibuprofen. We must try ...
The intestinal epithelium contains various rare cell types, including tuft cells and enteroendocrine cells51. Ayyaz et al. conducted scRNA-seq to profile the regenerating mouse intestine and discovered a distinct quiescent cell type called revival stem cell (revSC)52, which is induced by tissue dam...
Especially, tissue samples of recurrent OCCC are rare, and therefore, the function of the cluster in recurrent OCCC remains unknown. In the present study, we identified remarkably decreased expression of chrXq27.3 miRNA cluster in recurrent and metastatic OCCC. Subsequently, in vitro analyses ...