version of M100. Review of the amoxicillin-clavulanate breakpoint forH. influenzaeandH. parainfluenzaedetermined that an MIC of 4 µg/mL (susceptible by the M100, 31stedition breakpoint) was not achievable with oral dosing of amoxicillin-clavulanate (the only ...
Susceptibilities of aminoglycoside were assessed based on previous breakpoints in CLSI M100-S32 in 2022 as well as the current breakpoints from the most recent CLSI MIC breakpoints in 2023. RESULTS. We evaluated 1,393 CRE isolates. Most isolates were Klebsiella pneumoniae [n=876 (62.9%)] and ...
The CLSI annual update of its M100 document is eagerly awaited every year. This year’s update, the M100-Ed33, was published in February, and will significantly affect clinical practices. Objective To highlight and explain the rationale of the changes and their clinical impact. Content The majo...