Kuha, S, Miettinen, E (1986) Long-term effect of clozapine in schizophrenia: a retrospective study of 108 chronic schizophrenics treated with clozapine for up to 7 years. Nord Psychistr Tidskr 40: pp. 225-230Kuha S., Miettinen E.: Long-term effect of clozapine in schizophrenia: a ...
Clozapine causes metabolic problems, such as weight gain, type two diabetes and blood sugar problems, high blood pressure, and raised cholesterol. It is known to cause weight gain in 30% of people who take it. These side effects can cause long-term harm and need to be managed. ...
High doses or long-term use of clozapine can cause a serious movement disorder that may not be reversible. The longer you use clozapine, the more likely you are to develop this disorder, especially if you are a woman or an older adult. ...
For patients with diseases, conditions, or medications that could exacerbate these effects, complete fall risk assessments when initiating antipsychotic treatment and recurrently for patients on long-term antipsychotic treatment. Seizures Seizure has been estimated to occur in association with clozapine use ...
Less common side effects of clozapine include: Disturbed sleep Nightmares Confusion Agitation Restlessness (akathisia) Fatigue Impairment of voluntary movement (akinesia) Muscle rigidity Involuntary muscle contractions (dystonia) Seizure Movement disorder associated with long-term antipsychotic use (tardive dys...
instability, which may lead to falls and, consequently, fractures or other injuries. For patients with diseases, conditions, or medications that could exacerbate these effects, complete fall risk assessments when initiating antipsychotic treatment and recurrently for patients on longÂterm ...
Lindstrom IH. The effects of long-term treatment with clo- zapine in schizophrenia: a retrospective study in 96 patients treated with clozapine for up to 13 years. Acta Psychiatr Scand 1987;77:524-529.Lindstrom LH. The effect of long-term treatment with clozapine in schizophrenia: a ...
Long COVID Is Taking Toll on Americans' Finances One Type of Blood Pressure Med May Help Prevent Post-Stroke Epilepsy More Health News » Summary Clozapine (Clozaril, Fazacio ODT, Versacloz) is a medication prescribed for the management of psychotic disorders such as schizophrenia. Side effe...
On long term administration clozapine selectively enhances central dopamine D 1 -receptor function and produces down-regulation of serotonergic S 2 -receptors in rodents. Biochemical and neurophysiological studies indicate that clozapine may act preferentially on mesolimbic and amygdaloid rather than neo...
refractory outpatients who had been assigned to clozapine in a double-blind, haloperidol-controlled, long-term (29-week) study(14). Clozapine responders were rated as less severely ill, had fewer negative symptoms, and had fewer extrapyramidal adverse effects at baseline compared with non-responders...