艰难类梭菌(Clostridioides difficile,C.difficile)是一种革兰氏阳性厌氧芽孢杆菌,属于条件致病菌,毒素A和毒素B是其主要致病因子,可损伤患者肠壁,诱发炎症反应。艰难类梭菌感染(Clostridioides difficileinfection,CDI)的常见临床症状为腹泻,也可伴有发热和腹痛等...
Clostridioides difficile infection: a changing treatment paradigmdoi:10.5114/pg.2024.136237CLOSTRIDIOIDES difficileFECAL microbiota transplantationDRUG developmentClostridioides difficile infection (CDI) poses a persistent challenge in healthcare, with substantial morbidity and mortality implica...
C difficilecan colonize the intestines of healthy people without causing infection and survive on surfaces in the hospital and soil for extended periods. Contaminated surfaces and medical equipment in healthcare facilities can become reservoirs forC difficilespores, potentially transmitting to patients if ...
Clostridioidesdifficileinfection Clostridioidesdifficileis a bacterium that causes inflammation and is known to be one of the most common hospital-acquired infections. Clostridioides difficile Clostridioides difficile(C. difficile) is a bacterium that causes inflammation of the colon.C. difficile...
Clostridioides difficile infection presents a unique treatment paradox for clinicians: Antibiotics are often both its cause and its cure. News December 08, 2023 5 min read Save Q&A: DIY fecal microbiota transplantation a risky game of ‘Russian roulette’ ...
1. Clostridioides difficile infection (CDI) in the pre-COVID-19 pandemic period In the last decades, Clostridioides (Clostridium) difficile has emerged as the main cause of healthcare-associated infective diarrhea, rapidly becoming an urgent global public health threat [[1], [2], [3]]....
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into the colon. It can be delivered through many means including colonoscopy or by enema, thus, bypassing the acidic environment of the stomach. Though the name sounds undesirable, this therapy has been found to be a safe and efficacious treatment forC. difficileinfection in numerous studies1,2...
Clostridioides difficile infection (CDI) is a major cause of infectious diarrhea among allogeneic hematopoietic stem cell transplantation (allo-HSCT) recipients. The relationship between CDI and acute graft-versus-host disease (aGVHD) has been a topic of interest, as these 2 conditions may influenc...
What do I need to know about a C. diff infection (CDI)?Clostridioides difficile, Clostridium difficile, or C. diff, is a bacterium that causes diarrhea, irritation, and swelling of the colon.How does C. diff spread?The bowel movement of a person with a CDI contains C. diff. ...