Has been used effectively for the management of major depressive disorder† [off-label].Despite comparable efficacy, the adverse effect profile (e.g., anticholinergic effects) of clomipramine may limit its usefulness relative to other antidepressants (e.g., TCAs, SSRIs)....
The effectiveness of Anafranil for long-term use (i.e., for more than 10 weeks) has not been systematically evaluated in placebo-controlled trials. The physician who elects to use Anafranil for extended periods should periodically reevaluate the long-term usefulness of the drug for the indiv...
2.3 Appearance white to off-white powder 2.4 Color/Form white to off-white 2.5 pKa pKa 9.38(H2O) (Uncertain) 2.6 Water Solubility H2O: 25?mg/mL 2.7 StorageTemp Sealed in dry,Room Temperature3. Use and Manufacturing3.1 Definition ChEBI: A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[...
2.6 Color/Form white to off-white 2.7 PH 3.5~5.0(100g/l,25℃) 2.8 Water Solubility H2O: 25?mg/mL 2.9 StorageTemp 2-8°C3. Use and Manufacturing3.1 Definition ChEBI: A hydrochloride resulting from the reaction of equimolar amounts of clomipramine and hydrogen chloride. One of the more...