Testosterone therapy is the first-choice treatment for male hypogonadism, with several side effects, that is, subfertility. Clomiphene citrate (CC) is an alternative off-label therapy for a certain group of hypogonadal males, especially for those with an active or future child wish. There...
Clomiphene Citrate CAS 50-41-9 WIKI information includes physical and chemical properties, USES, security data, NMR spectroscopy, computational chemical data and more.
Uses Clomiphene Citrate is an unducer of ovulation. It is a selective estrogen receptor modulator, which acts by inhibiting the action of estrogen on the pituitary. Clomiphene Citrate is also an activator of PKC and Gonad-stimulating principle. Manufacturing Process A mixture of 20 g of 1-[p-...
Each white scored tablet contains 50 mg clomiphene citrate USP. The tablet also contains the following inactive ingredients: corn starch, lactose, magnesium stearate, pregelatinized cornstarch, and sucrose. Uses for Clomid CLOMID is indicated for the treatment of ovulatory dysfunction in women desiring...
A group of 12 sterile, azoospermic mink males were treated with clomiphene citrate (10 mg/kg/day) for 10 days during the mating season; 50% of the males showed improved sperm counts already after 2 days of treatment and the maximum effect was seen 4–6 days after the start of the tr...
., clomiphene citrate in conjunction with other ovulation-inducing drugs). Similarly, there is no standard clomiphene citrate regimen for ovulation induction inin vitrofertilization programs to produce ova for fertilization and reintroduction. Therefore, clomiphene citrate is not recommended for these uses...
FIG. 2 shows the chemical structure of clomiphene citrate. FIG. 3 is a graphic demonstration of the time course of serum testosterone levels with Clomid, Enclomid and Zuclomid. FIG. 4 is a graphic demonstration of the time course of cholesterol levels in baboon males treated with Clomid, En...
Therefore, clomiphene citrate is not recommended for these uses. CONTRAINDICATIONS Hypersensitivity Clomiphene citrate is contraindicated in patients with a known hypersensitivity or allergy to clomiphene citrate or to any of its ingredients. Pregnancy Clomiphene citrate use in pregnant women is ...
The effect of clomiphene citrate in the treatment of subfertile males with body mass index (BMI) ≥ 25 kg/m2Hypophysectomized and sham-operated gravid goldfish were injected with clomiphene citrate. Only the sham-operated fish ovulated. This indicates that clomiphene citrate acts through the ...
The effect of clomiphene citrate in the treatment of subfertile males with body mass index (BMI) ≥ 25 kg/m2doi:10.1016/j.fertnstert.2015.07.038B. PatelT. ShahD. ShinFertility and Sterility