Cell line data 细胞系数据 Para_01 以下使用的DepMap细胞系数据(depmap.org/portal/):突变(CCLE_mutations.csv),拷贝数(CCLE_segment_cn.csv),全局TMT蛋白质组学,66来自Broad和Sanger研究的组合CRISPR KO依赖性数据(CRISPR_gene_effect.csv),18 Sanger的癌症药物敏感性基因组(GDSC)药物反应数据67以及Broad的混合...
Study of the molecular and cellular mechanisms acting in CLL, including Monoclonal B-cell Lymphocytosis (MBL) Published over 350 manuscripts in peer-reviewed journals 参考文献: 1.Eichhorst B, Niemann CU, Kater AP, et al. ...
[10] Archibald et al. Real-World First-Line Treatment and Outcomes of Patients with Chronic Lymphocytic Leukemia (CLL) Treated with Bruton Tyrosine Kinase Inhibitor (BTKi) or B-Cell Lymphoma 2 (BCL2) Therapy. Blood (...
H. 1999. Infrared spectroscopic study of bryostatin 1-induced membrane alterations in a B-CLL cell line. Leukemia 13:1273.Liu KZ, Schultz CP, Johnston JB, Beck F, Al-Katib AM, Mohammad RM, et al. Infrared spectroscopic study of bryostatin 1-induced membrane alterations in a B-CLL cell ...
[7]Rawstron AC, Kreuzer KA, Soosapilla A, et al. Reproducible diagnosis of chronic lymphocytic leukemia by flow cytometry: An European Research Initiative on CLL (ERIC) & European Society for Clinical Cell Analysis (ESCCA) Harmonisation project. Cytometry B Clin Cytom. 2018 Jan;94(1):121-12...
The most common side effects of IMBRUVICA® in adults with B-cell malignancies (CLL/SLL and WM) include low platelet count; diarrhea; tiredness; muscle, bone, and joint pain; low white blood cell count; rash; low red blood cell count (anemia); bruising; and nausea. The most common si...
Cell Line from Henrietta Lacks Human Papilloma Virus HSIL High Squamous Intraepithelial Lesions HTLV-1 Human T-Cell Leukemia Virus Type-1 Interferon IHC Immunohistochemistry IKK Iκb Kinase IL Interleukin Ile Isoleucine ISH In SituHybridization
The capacity of macrophages to support CLL cell survival has been well established in numerous in vitro studies with primary CLL cells and has been further validated in in vivo studies with Eμ-TCL1–derived murine CLL cells or the human CLL cell line MEC1.43, 44, 45, 46,52, 53, 54,...
CLL/SLL is a slow-growing blood cancer. The cancer occurs in B cells, a type of white blood cell. B cells are an important part of your immune system, which defends your body against infection. In CLL/SLL, abnormal B cells grow and spread in the bloodstream. They can also crowd out...
CALQUENCE® (acalabrutinib) is a BTK inhibitor indicated for the treatment of adult patients with R/R Mantle Cell Lymphoma (MCL) and Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL).