Thisreview summarizes the history of chemical structure of colchicine and presents someof its analogues. Furthermore, it shows binding mechanism with target protein whencolchicine is used as a therapeutic drug, and gives a light spot on some studies thatdiscuss the safe use of colchicine....
The use of colchicine for acute gouty arthritis dates to ancient times. In recent years, colchicine also has been used successfully for various other rheumatic and nonrheumatic conditions. Colchicine is a safe drug when used according to established therapeutic guidelines. However, toxicity can be co...
disease symptom profile analysis, and multivariate treatment protocols. Together with the theory of Yin and Yang, the Five Elements Theory forms the essential philosophy and methodology of TCM. As mentioned previously, TCM practitioners use a combination of the theories of Yin/Yang ...
such as the use of cul- tured somatic cells, of colchicine treatment to accumulate metaphases and to contract the chromosomes so as to dis- tinctly separate them, of hypotonic solution to spread them well, and of squashing so as to flatten them to the same microscope observation plane. Th...
2025 KRAS Mutation Status and Outcomes in Metastatic Pancreatic Adenocarcinoma Research January 7, 2025 Sign Up for Emails Based on Your Interests Others Also Liked We recommend Preliminary results of clinical use of colchicine in COVID-19 treatment Rafael Silvestre Knack, BMJ Case Reports, 2021 Cand...
Quantitative CCTA analysis has also been used to evaluate the effects of optimal medical therapy and colchicine in patients with recent ACS, demonstrating favorable effects on plaque characteristics over time independent of high-intensity statin therapy (76). Future studies should further assess the ...
Postoperative use of colchicine prevented these complications in a single trial. Objective To determine the efficacy and safety of perioperative use of oral colchicine in reducing postpericardiotomy syndrome, postoperative AF, and postoperative pericardial or pleural effusions. Design, Setting, and ...
Abstract The variables determining clinical response to NSAIDs are reviewed—the only one of major importance being severity of pain when treatment is commenced. Age, sex and disease-dependent variables are perhaps of importance, as is the nature of the tablet or capsule, but thein vitropotency ...
This study aimed to (1) determine the relative forgiveness (RF) of allopurinol with hypothetical and real-life implementation patterns in people with gout, (2) explore the use of RF as a means of identifying suboptimal implementation patterns, (3) assess the impact of suboptimal implementation ...
Effect of colchicine vs standard care on cardiac and inflammatory biomarkers and clinical outcomes in patients hospitalized with coronavirus disease 2019. JAMA Netw Open. 2020;3(6):e2013136-e2013136. ArticlePubMedGoogle ScholarCrossref 22. Sterne JAC, Murthy S, Diaz JV, et al...