Designed to be a practical handbook on clinical trial management in these key therapeutic areas, 'Clinical Trials in Rheumatoid Arthritis and Osteoarthritis' is aimed at principal investigators pharmaceutical physicians and other pharmaceutical staff involved in the design, conduct and monitoring of these ...
Designed to be a practical handbook on clinical trial management in these key therapeutic areas, Clinical Trials in Rheumatoid Arthritis and Osteoarthritis is aimed at principal investigators pharmaceutical physicians and other pharmaceutical staff involved in the design, conduct and monitoring of these ...
doi:10.1038/ncprheum0114Rachel MurphyNature Clinical Practice Rheumatology
系统标签: trials arthritis rheumatoid prompt trial stratification ClinicaltrialsaimingtopreventRheumatoidArthritiscannotdetectpreventionwithoutadequateriskstratification;thePROMPT-trialasexampleRunninghead:ImportanceofriskstratificationintrialsaimedatpreventionofRALeonieEBurgers1,MD.,CorneliaFAllaart1,MD,PhD.,TomWJHuizinga...
Its effect on upregulation of inflammatory events within the joints makes it an appropriate pharmacological target in rheumatoid arthritis (RA). Infliximab, an anti-TNF treatment, has been successful in clinical trials in reducing TNFα induced production of other inflammatory mediators, thereby ...
Rheumatoid arthritis (RA) clinical trials often include at least 10 measures of disease activity (e.g., tender and swollen joint counts, erythrocyte sedime... DT Felson - 《Journal of Rheumatology》 被引量: 1844发表: 1993年 Which outcome measures should be used in rheumatoid arthritis clinical...
Arthritis Rheum 2006;54 Suppl:S375.PINCUS T, BERGMAN M, YAZICI Y, RAGHU- PATHI K, HINES P, MACLEAN R: Rheumatoid arthritis patient index data (RAPID): perfor- mance in two abatacept clinical trials of 4 absolute indices of 2-5 core data set measures based on patient reported outcomes ...
Clinical Trials Clinical trialsare research activities that involve the administration of a treatment or prevention regimen to humans to evaluate its safety and efficacy.1In general, these trials involve a comparison of clinical outcomes of a group of patients receiving treatment with the outcomes of ...
ClinicalTrials.gov, https://clinicaltrials.gov/study/NCT03410043 (2018). Elamin, Y. Y. et al. Local consolidation therapy (LCT) after first line tyrosine kinase inhibitor (TKI) for patients with EGFR mutant metastatic non-small-cell lung cancer (NSCLC). Clin. Lung Cancer 20, 43–47 (...
Rheumatoid arthritisdisease activityclinical evaluationoutcomesQuantitative clinical monitoring of patients with musculoskeletal conditions should be included in the infrastructure of every clinical practice. Quantitative monitoring improves the physician's capacity to assess and document a patient's clinical status...