根据全球临床试验收录网站clinicaltrials和中国临床试验登记平台chinadrugtrials,3月共12款创新药进入III期阶段,其中5款来自中国药企。这些在研药物覆盖靶点不乏HER2、CLDN18.2、IL-5等热门靶点,也包括apo(a)和C1s这类新颖靶点。本文筛选其中6款重点产品加以介绍。 相关研究报告免费下载:医药魔方-2023年度全球创新药十大...
The NeurologyLive® movement disorders clinical focus page is a source for all the latest news regarding the clinical care of patients with Parkinson disease, essential tremor, Huntington disease, dystonia, ataxia, and more. This page features podcasts, videos, and news about FDA actions, study ...
Future Outlook for Alzheimer’s Disease Prevention Trials in Alzheimer’s Disease Data from Other Emerging Alzheimer’s Disease Treatment Options from CTAD 2022 Other Anti-Amyloid Antibody Agents for Treatment of Alzheimer’s Disease Lecanemab for Treatment of Alzheimer’s Disease Management of Amyloid...
Notably, AMAN is the predominant type in northern China, accounting for 55.3% of GBS cases, while AIDP prevails in southern China. Intravenous immunoglobulin (IVIG) and plasma exchange (PE) are the only known immunotherapeutic approaches that accelerate recovery from GBS. Clinical trials have ...
(SCIG) versus placebo in maintenance treatment of chronic inflammatory demyelinating polyneuropathy (CIDP) during the PATH study.Background: In CIDP, quality of life aspects like TS and WP are of importance in clinical trials in addition to efficacy and safety.Design/Methods: Patients (n=172) ...
ICANS did not manifest in early mouse models but emerged during clinical trials. Therefore, it becomes even more important to understand the precise pathomechanisms in the human central nervous system and to verify the findings obtained through animal models. For these inquiries, a standardized ...
On the other hand, CIDP is a chronic disease, and PP/PE or IVIG is often needed on a chronic basis. Physicians titrate the frequency of therapies to the recurrence of symptomatology. Controlled clinical trials have failed to validate the effectiveness of PP/PE as a treatment of systemic ...
157 There is a need for extensive and methodologically robust randomized controlled trials to determine the effectiveness of vitamin D supplementation in managing PDPN. Conclusion Several challenges exist in the management of PDPN. The condition is highly prevalent and is o...
https://clinicaltrials.gov/study/NCT03926130?tab=results#publications Jairath V, Sands BE, Bossuyt P, Farraye F, et al. OP35 Efficacy of mirikizumab in comparison to ustekinumab in patients with moderate to severe Crohn’s disease: Results from the phase 3 VIVID 1 study. J Crohns...
Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, is a sporadic or inherited neurodegenerative disease of upper motor neurons (UMNs) and lower motor neurons (LMNs).