The post operative pain is also assed using PRO instrument. The U.S. Food and Drug Administration (FDA) have laid down standards for developing these instruments.KussVice PresidentMichaelVice PresidentApplied Clinical Trials
chronic pain clinical trials: IMMPACT Recommendations. J Pain 2008;9(2):105-21.Turk, D. C. and Dworkin, R. H. (2008) Chronic Pain Clinical Trials: IMMPACT Recommendations. In: Raj's practical management of pain. pp. 1201 - 1217. Eds. H. T. Benzon, J. P. Rathmell, C. L. Wu,...
Katz, N. Methodological issues in clinical trials of opioids for chronic pain. Neurology 65, S32–S49 (2005). Article Google Scholar Keller, S. et al. Validity of the brief pain inventory for use in documenting the outcomes of patients with noncancer pain. Clin. J. Pain 20, 309–318 ...
Clinical Trials in Pain Relief : 10 Challenges CT Register 被引量: 1发表: 1999年 Clinically important changes in acute pain outcome measures: a validation study. Measures of pain intensity and pain relief are commonly used outcomes in therapeutic clinical trials. Recent studies of the properties ...
Although a number of measures of pain qualities exist, little research has examined the potential for these measures to identify the unique effects of pain treatments on different pain qualities. We examined the utility of the Neuropathic Pain Scale (NPS) for assessing changes in pain qualities aft...
Canadian Centre for Clinical Trials is a contract research organization with more than a decade of experience, qualified experts, a personalized approach, and competitive prices. We will provide all tools to support your clinical trial all the way. In addition, CCCT conducts its own independent res...
Tapentadol prolonged release for chronic pain--a review of clinical trials and five years of routine clinical practice data. Pain Pract. 2016. https://doi.org/10. 1111/papr.12515.Tapentadol Prolonged Release for Chronic Pain:A Review of Clinical Trials and 5 Years of Routine Clinical Practice...
Buprenorphine for chronic pain: a review of the clinical effectiveness. Ottawa (ON); Canadian Agency for Drugs and Technologies in Health; 2017. Sittl R, Griessinger N, Likar R. Analgesic efficacy and tolerability of transdermal buprenorphine in patients with inadequately controlled chronic pain rela...
Pain is the most common physical symptom in primary care, accounting for an enormous burden in terms of patient suffering, quality of life, work and social... K Kroenke,E Krebs,J Wu,... - 《Contemporary Clinical Trials》 被引量: 67发表: 2013年 Issues in the design of a randomized non...
Efficacy Small controlled trialsAnalgesic effect independent of mood effect Large randomized trials for depression and anxietyLittle or no efficacy for direct pain reduction Large randomized trials for depression and anxietySmall controlled studies for chronic pain Small randomized controlled trials for depress...