The meaning of CLINICAL TRIAL is a scientifically controlled study of the safety and effectiveness of a therapeutic agent (such as a drug or vaccine) using consenting human subjects.
Clinical trial definition: the scientific investigation of a new treatment that has shown some benefit in animal or laboratory studies, but that has not yet been proven effective in humans.. See examples of CLINICAL TRIAL used in a sentence.
The meaning of CLINICAL is of, relating to, or conducted in or as if in a clinic. How to use clinical in a sentence.
Methods and Findings: We scanned all trials in ClinicalTrials.gov marked with the "terminated" status (N=3122), meaning the trial had been stopped before the scheduled end date. Under the current reporting framework, any number of reasons may be given for termination, and these need not ...
Clinical significance or importance refers to the actual treatment effect that will determine whether the results of the trial or meta-analysis are likely to impact current medical practice (see the example in Fig. 2). With large sample sizes, even small treatment effects can appear statistically ...
According to the International Committee of Medical Journal Editors (ICMJE) a clinical trial is “any research project that prospectively assigns people or a group of people to an intervention, with or without concurrent comparison or control groups, to study the relationship between a health-related...
A main methodological challenge for the randomized trial is to avoid bias once patients have been allocated. Other challenges include obtaining clinically relevant interventions and outcomes, risk of attrition, ensuring an adequate number of patients for statistical power, and risk of selective report...
Both tissue-of-origin studies and tumor-agnostic/genomic-based studies are drug-centered, meaning that the trial offers the same drug(s) to each patient and the patient must fit the trial. Patients are chosen for the trial based on their commonalities, that is, whether they have the same ...
only for CTGOV2: object history with a historic version of the trial and with history_version, which contains the fields version_number (starting from 1) and version_date all original fields as provided by the register for that trial (see examples below)For...
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