The Simcyp Simulator is the leading physiologically based pharmacokinetics (PBPK) platform for determining first-in-human dosing, optimizing clinical study design, evaluating new drug formulations, setting the dose in untested populations, performing virtual bioequivalence analyses, and predicting drug interact...
That tide is starting to turn as more companies across the clinical trial value-chain incorporate software into their product offering. A recent study found that64% of researchers have used digital health tools in their clinical trials, and 97% plan to use these tools in the next 5 years. T...
OpenClinica aims to empower data managers, clinical researchers, and study participants by enabling more efficient clinical research. The major strengths of automation are in engagement and speed of tasks. As such, this solution has the potential to save a substantial amount of working hours. 10 ...
For this prospective, pragmatic study, the primary outcome being measured is the number of new healthcare actions after return of the genome-informed risk assessment. This paper describes (1) identification, selection and optimization of the PRSs that are included in the study; (2) calibration ...
All computations were performed using the SPSS software (25.0.0, IMB Corp., Armonk, NY, USA). Ethics approval All procedures performed in this study involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964...
You can use RDC Onsite to collect, perform immediate validation on, review, verify, approve, and report clinical data collected during a patient visit in a clinical study. Patient data is stored in the Oracle Clinical database. You can use Oracle Clinical features including batch validation, ...
Correct - these are the two main functions that I expect users to interact with as they abstract away all the efforts of doing the simulation study. get_nmb_sampler() may be helpful to users to create the inputs for these functions (fx_nmb_training and evaluation) and all other functions...
Improve productivity by streamlining, automating, and reporting on clinical trial operations data across all study management processes.Explore Siebel CTMS (PDF)Oracle’s CTMS manages your clinical trial data. See BeiGene’s story (4:50) Siebel Clinical Trial Management System product features ...
The interpretation of model predictions, especially in situations demanding transparency and trust, relies on our capacity to grasp the importance of individual features. To study the ability of ChatGPT to provide metrics of explainability, we utilized the SHapley Additive exPlanations (SHAP)26analysis ...
It is therefore of vital importance that such changes be documented and identified by software version and that a robust post-deployment surveillance plan is in place. This study is set in the current context of AI in health; therefore, several limitations should be noted. First, there are ...