Sickle cell disease ( SCD ) is a group of genetic disorders that cause an abnormal Hb molecule ( Hb S) that transforms RBCs into sickle-shaped cells, resulting in chronic anemia , vasoocclusive episodes, pain , and organ damage. Epidemiology[2] Most common form of intrinsic hemolytic anemia...
L. ( 1951 ). ‘ Acute hemolytic anemia due to ingestion of naphthalene moth balls . Pediatrics , 7 , 722 .Mackell JV, Rieders F, Brieger H (1951) Acute hemolytic anemia due to ingestion of naphthalene moth balls. I. Clinical aspects. Pediatrics 7:722-727...
and α-methyldopa andhemolytic anemia. Spontaneous notifications led to the recognition of important ADRs, including the liver damage caused by amiodarone, halothane- and α-methyldopa-induced forms of hepatitis, the neurologic changes caused by nalidixic acid, the hepatic lesions associated withibufenac...
Vitamin C (VitC), also known as ascorbic acid or ascorbate, is an essential water-soluble vitamin that plays an important role in human physiology. Most of its physiological functions involve its ability to act as an antioxidant or as a cofactor for a wide variety of enzymatic reactions, ther...
Acute graft versus host disease For the treatment of acute graft versus host disease when either of the following criteria is met: Member has experienced an inadequate response to systemic corticosteroids; or Member has an intolerance or contraindication to corticosteroids; Polymyalgia rheumatica (PMR) ...
Hemolytic uremic syndrome; or Hyperglobulinemias, including (but not limited to) multiple myelomas, cryoglobulinemia, and hyperviscosity syndromes; or Hypertriglyceridemia-induced acute pancreatitis when the following criteria are met: Serum triglyceride level greater than 1,000 mg/dL; and Lipase greater...
The effectiveness of convalescent plasma and hyperimmune immunoglobulin for the treatment of severe acute respiratory infections of viral etiology: a systematic review and exploratory meta-analysis. J Infect Dis. 2015;211(1):80-90. doi:10.1093/infdis/jiu396 PubMedGoogle ScholarCrossref 87...
Monitor patients closely for symptoms and signs that may be clinical manifestations of underlying immune-mediated adverse reactions. Early identification and management are essential to ensure safe use of anti–PD-1/PD-L1 treatments. Evaluate liver enzymes, creatinine, and thyroid functio...
(1.5%), myositis, pancreatitis, hemolytic anemia, partial seizures arising in a patient with inflammatory foci in brain parenchyma, adrenal insufficiency, Guillain-Barré syndrome, myasthenia gravis, vasculitis, sarcoidosis and encephalitis. In addition, myelitis and myocarditis were reported in other ...
Comparing the hemolytic activities of 292 isolates showed, surprisingly, that ABSA strains were significantly more likely to be highly hemolytic compared to other strains. In contrast, there were no differences between the relative abilities of strains from the different clinical history groups to form...