Associated signs Aggression as a presenting problem may be the result of organic disease, particularly disorders affecting the brain. In these patients the onset of aggressive behavior is usually acute and may b
Owing to the general presence of strong anti-A alloantibodies in type B cats, type A blood given to a type B cat results in life-threatening acute hemolytic transfusion reactions. Immediate withdrawal of a transfusion and supportive care may save a patient. Other transfusion reactions, unrelated...
Sickle cell disease ( SCD ) is a group of genetic disorders that cause an abnormal Hb molecule ( Hb S) that transforms RBCs into sickle-shaped cells, resulting in chronic anemia , vasoocclusive episodes, pain , and organ damage. Epidemiology[2] Most common form of intrinsic hemolytic anemia...
Drug allergy encompasses a spectrum of immunologically-mediated hypersensitivity reactions (HSRs) with varying mechanisms and clinical presentations. This type of adverse drug reaction (ADR) not only affects patient quality of life, but may also lead to delayed treatment, unnecessary investigations, and ...
Drug allergy encompasses a spectrum of immunologically-mediated hypersensitivity reactions (HSRs) with varying mechanisms and clinical presentations. This type of adverse drug reaction (ADR) not only affects patient quality of life, but may also lead to
Current practices vary widely regarding the immunological work-up and management of patients affected with defects in thymic development (DTD), which inclu
Lupus-specific cutaneous manifestations associated with the three subtypes of cutaneous lupus (CLE) described in Types of Lupus: acute CLE, most often manifesting as a non-discoid malar rash (see Figure 2-2A), subacute CLE, commonly presenting with nonindurated psoriasiform and/or annul...
Monitor patients closely for symptoms and signs that may be clinical manifestations of underlying immune-mediated adverse reactions. Early identification and management are essential to ensure safe use of anti–PD-1/PD-L1 treatments. Evaluate liver enzymes, creatinine, and thyroid functio...
Aetna will not provide coverage for members withanyof the following exclusions: Pediatric members with TMB-H central nervous system cancers; Members who have experienced disease progression while on programmed death receptor-1 (PD-1) or PD-L1 inhibitor therapy (other than when used as second-line...
Willi, et al., “Identification, Molecular Characterization, and Experimental Transmission of a New Hemoplasma Isolate from a Cat with Hemolytic anemia in Switzerland”, Journal of Clinical Microbiology, vol. 43, No. 6, p. 2581-2585, 2005. Inokuma, et al., “Molecular Survey of Mycoplasma ...