Nowadays, the implementation of findings discovered in clinical trials into mainstream medicine remains an arduous and lengthy process and the clinical trials themselves represent only a small stage of the process of developing a new drug from research stage to launch in the marketplace. On average,...
Flowchart of study subjects Full size image Fig. 2 Change in height of the study population after rhGH treatment. rhGH: recombinant human growth hormone Full size image Fig. 3 Height SDS of the study population after rhGH treatment. Height SDS: height standard deviation scores; rhGH: recombinant...
This research team approved the "methodologies and procedures for developing clinical practice guidelines of organic integration TCM and WM" in the China Standardization Association, aiming to standardize the development process of guidelines for integrated TCM and WM, and develop guidelines that can ...
However, with advancements in tumour research, surgical techniques, radiation therapy, chemotherapy, and the application of multidisciplinary teams, the clinical efficacy of the modified Tokuhashi scoring system has gradually declined over time [13]. With respect to the surgical treatment group analysed ...
Flowchart of trials Full size image Number and proportion of retroactively prospective trials We found that 235 out of 11,908 trials (2.0%) had been retroactively prospectively registered, with a start date in the past at the time the study was registered (i.e., retrospective registration), an...
Study flowchart Full size image Flow diagram of retrospective cross-sectional study with inclusion and exclusion criteria. FDAAA: The Food and Drug Administration Amendment Act, FDA: The Food and Drug Administration. Sample Inclusion criteria are shown in Fig. 1. Requirements for considering trials as...
Study flowchart. MIMIC, Medical Information Mart for Intensive Care Full size image Clinical characteristics Of the 1104 patients (Table 1), the mean age was 63 (± 18) years, 603 patients (54.6%) were women, and most patients (63.0%) were non-Hispanic White. Regarding risk factors for...
Study flowchart showing the process of constructing nomogram to predict the overall survival (OS) of second primary malignancies (SPMs) after prostate cancer (PCa). Full size image Statistical analysis To explore the association between clinicopathological variables and OS of SPM, we performed univariate...
This process is described in the Supplemental Text, Methods, and Fig. S4. The selected concentrations are included in Supplementary Data 4. Fig. 3: Trial selection pipeline for clinical validation. Flowchart detailing how completed, phase III cancer clinical trials were selected for the clinical ...
and 6) performance evaluation. The original AutoScore structure is elaborated inthis articleand its flowchart is shown in the following figure. AutoScore was originally designed for binary outcomes and later extended tosurvival outcomesandordinal outcomes. AutoScore could seamlessly generate risk scores usi...