Seizures are a common initial manifestation, most frequently infantile spasm. Chevrie et al reported 97% of patients had infantile spasm, and most of these had seizures when younger than 3 months. [14] Additional seizure types noted include hemiconvulsions, complex partial seizures, and focal moto...
CONCLUSIONS: Signs and symptoms of nephrogenic systemic fibrosis vary over time and between patients. The disease leads to severe disability in a significant proportion of affected patients. Intensive physiotherapy may limit the development of contractures. 展开 ...
Trainees with disabilities in health-related professions are often subjected to structural ableism in medicine: the discriminatory manifestation of lowered expectations towards people with disabilities by medical professionals. In this case study, I reflect on my experiences as the first in...
Clinical manifestations of toxoplasmosis in patients with AIDS Brain involvement (ie, toxoplasmic encephalitis), with or without focal CNS lesions, is the most common manifestation of toxoplasmosis in individuals with AIDS. Clinical findings include the following: Altered mental state Seizures Weakness...
The first clinical manifestation of myocardial ischemia or infarction may be sudden ... N Luqman,RJ Sung,CL Wang,... - 《International Journal of Cardiology》 被引量: 118发表: 2007年 Clinical Implications of Alpha-fetoprotein in Chronic Hepatitis C Chronic hepatitis C (CHC) shows a significant...
Tuberous sclerosis complex (TSC) is an autosomal dominant disorder characterized by the presence of proliferative lesions throughout the body. Management of TSC is challenging because patients have a multifaceted systemic illness with prominent neurological and developmental impact as well as potentially sev...
Glial fibrillary acidic protein (GFAP), an intracellular type III intermediate filament protein, provides structural support and maintains the mechanical integrity of astrocytes. It is predominantly found in the astrocytes which are the most abundant subtypes of glial cells in the brain and spinal cord...
distribution in HEK293T cells. This observation indicates that the disruption of the NLS might only contribute to a portion of the phenotype manifestation. The loss of the functional domain at the C-terminus, or potential anomalies in the 3D structure of ADNP protein complex, could play a ...
The diagnostic status of the participants was obtained by latent class analysis. Logistic regression was used to identify aetiological factors with the manifestation of sedentary lifestyle, considering a significance level of 5%. Results A total of 57.8% of the study participants met the diagnostic ...
Family trees and clinical manifestation. Panel A: Family trees of the five families. Panel B: Duration of epilepsy (E) and of paroxysmal exertion-induced dyskinesia (PED) throughout lifespan is shown by gray and blue lines respectively. For each patient, current age and intelligence quotient ar...