Because the pathologic damage may involve any area of the CNS, the location of the lesions also play a role in symptom production.doi:10.1016/j.ncl.2004.09.003LublinFred D.Elsevier Inc.Neurologic ClinicsLublin FD.Clinical features and diagnosis of multiple sclerosis. Neurol Clin, 2005, 23(1):...
The diagnostic criteria for multiple sclerosis (MS) rely on clinical, paraclinical, and radiographic findings of limited specificity. Many disorders mimic MS, and the decision of when to investigate an alternative diagnosis can be challenging. Reliance on extensive ancillary testing to exclude potential...
Due to the heterogeneous nature of the disease, it is a challenge to capture disease activity of multiple sclerosis (MS) in a reliable and valid way. There
We present a case with diagnosis of multiple sclerosis done on clinical criteria and proved by autopsy. The morphological aspects of the lesions are well known and often related in the literature. Our objective is to describe the first necropsy among 30500 done at Santa Casa de So Paulo in a...
HP, Lublin FD, McFarland HF, Paty DW, Polman CH, Reingold SC, Sandberg-Wollheim M, Sibley W, Thompson A, van den Noort S, Weinshenker BY, Wolinsky JS: Recommended diagnostic criteria for multiple sclerosis: guidelines from the international panel on the diagnosis of multiple sclerosis. Ann...
National clinical guideline for diagnosis and management in primary and secondary care Excerpt Multiple sclerosis (MS) is a condition of the central nervous system (brain and spinal cord) that usually starts in early adult life. Once present the disease never goes; there is no cure and the ...
News of a celebrity's remission from multiple sclerosis after undergoing stem cell transplantation, along with new research into other treatment issues, led to this week's top trending clinical topic.
83% of adjudicated cases had 2 of 3 adjudicators agreeing on the diagnosis and 17% had no consensus.Conclusions: Despite the existence of diagnostic criteria for multiple sclerosis, there is great heterogeneity among MS experts in the application of these criteria. This heterogeneity has significant...
(HealthDay)—Various clinical symptoms precede the diagnosis of multiple sclerosis (MS) by several years, according to a study published online May 8 in the Annals of Neurology.
MRI in the Diagnosis and Monitoring of Multiple Sclerosis: An Update Article23 July 2015 Introduction The high sensitivity of MRI in the depiction of plaques in the brain and spinal cord has made this technique the most important paraclinical tool for the diagnosis of multiple sclerosis (MS). ...