lncRNA MIAT functions as a competing endogenous RNA to upregulate DAPK2 by sponging miR-22-3p in diabetic cardiomyopathy. Cell Death Dis. 2017;8: e2929. Article CAS PubMed PubMed Central Google Scholar Liu Y, Zhu Y, Liu S, Liu J, Li X. NORAD lentivirus shRNA mitigates fibrosis and ...
Jager T, Barbary S, Dap F, Dautel G. [Evaluation of postoperative pain and early functional results in the treatment of carpometacarpal joint arthritis. Comparative prospective study of trapeziectomy vs. MAIA((R)) prosthesis in 74 female patients]. Chir Main. 2013;32(2):55–62. Article CAS...
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DNM1 as a case example using the candidate-gene criteria In September 2014, we reported a de novo missense altera- tion in the DNM1 gene in a 10-month-old boy presenting with early-onset infantile spasms, hypotonia, developmental delay, and microcephaly. At the time, DNM1 was a ...
DAPK1,CR2,KIF16B,NPIPB15,SYTL2,ZNF91, andKIAA0586. With an unsupervised clustering algorithm, we propose a subtyping strategy that classisfies CRC patients into four genomic subtypes with distinct clinical characteristics, including hypermutated, chromosome instability with high risk, chromosome ...
As NK cells have their own intertwined activating and inhibitory receptors to control NK cell activation and cytotoxicity, it is proposed that using NK-specific intracellular signaling domains, such as the adapter molecule DAP10 or ITAM-containing signaling domains, such as DAP12 and 2B4, may improv...
these investigators included sensitivity analyses in which the biopsy outcomes of these participants were omitted. The effect on the results was small. Other safety mechanisms could be used -- for example, biopsy on the basis of PSA alone (e.g., PSA greater than or equal to 10 ng/ml) or...
Basal-like constitutes an important molecular subtype of breast cancer characterised by an aggressive behaviour and a limited therapy response. The outcome of patients within this subtype is, however, divergent. Some individuals show an increased risk of
[55]. However, smaller differences may be important. For example, a 6-month randomized controlled trial of 210 subjects with T2D and baseline HbA1c of 7.1% showed that a 14% reduction in diet glycaemic index reduced HbA1c by 0.32% relative to control (p < 0.001) [56], an effect ...
Positive (mmPpib, 313918) and negative (mm-DapB, 312038) control probes were implemented to ensure staining integrity and accuracy. Images were acquired using an Olympus BX51 and Zen2 Lite Blue imaging software at ×20 magnification. Gene signatures The majority of the gene set signatures, ...