Multiple endocrine neoplasia type 1 (MEN1) is a rare syndrome characterized by the co-occurrence of primary hyperparathyroidism, duodenopancreatic neuroendocrine tumours (NETs) and/or pituitary adenomas. MEN1 can predispose patients to other endocrine and non-endocrine tumours, such as cutaneous ...
Clinical aspects, pathomorphology and therapy. represent a heterogeneous spectrum of subtypes and may be associated with von Recklinghausen's disease type I (VRD) and multiple endocrine neoplasia type I... H Witzigmann,C Loracher,F Geissler,... - 《Langenbecks Arch Surg》 被引量: 89发表: ...
Clinical aspects of intraductal papillary mucinous neoplasm of the pancreas Intraductal papillary mucinous neoplasm (IPMN) is a spectrum of neoplasia in the pancreatic duct epithelium characterized by cystic dilation of the main an... M Tanaka,K Kobayashi,K Mizumoto,... - 《Journal of Gastroenterolog...
In this setting, the pathologist plays a critical role in patient management and treatment selection.In this review, we provide a comprehensive overview of the current knowledge of molecular aspects of prostate cancer and their potential utility in the context of different therapeutic approaches. ...
No adverse histopathological effects on the transplanted HuCNS-SC, such as neoplasia, cystic structures, or immune cell infiltration, were apparent. A molecular analysis was performed on several samples from the post-mortem brains using quantitative PCR analysis to identify the presence of donor cells...
The technical aspects of modified condylotomy are simple and familiar to surgeons comfortable with intraoral vertical ramus osteotomy. Satisfactory pain relief following modified condylotomy for non-reducing disc displacement (NRDD) demonstrate that disc reduction is not a pre-requisite. However, when ...
The clinical manifestations of renal disease Nephritic syndrome: - acute onset grossly visible hematuria - mild proteinuria -azotemia -Edema -Hypertension Nephrotic syndrome -heavy proteinuria (excretion of greater than 3.5 g of protein/day in adults) -Hypoalbuminemia -severe edema - hyperlipidemia, ...
As discussed above, STAT3 participates in almost all aspects of immune escape and tolerance in TME. Consequently, combination STAT3 inhibition with immune checkpoint inhibitor is a promising strategy to improve the clinical response in tumor patients. STX-0119, a STAT3 dimerization inhibitor, combined ...
Gimm O. Multiple endocrine neoplasia type 2: clinical aspects. In: Dahia PLM, Eng C, editors. Genetic disorders of endocrine neoplasia. 1st ed. Basel: Karger, 2001. pp.103-30.Gimm O. Multiple endocrine neoplasia type 2: clinical aspects. Front Horm. 2001;28:103-30....
Gimm O. Multiple Endocrine Neoplasia Type 2: Clinical Aspects. In: Dahia PLM, Eng C. Genetic Disorders of Endocrine Neoplasia. 1st ed. Phila- delphia: Front Horm Res Basel Karger; 2001. p. 103- 30.Gimm O (2001) Multiple endocrine neoplasia type 2: Clinical aspects. Front Horm Res 28:...