Culver, Kenneth W., “Clinical Applications of Gene Therapy for Cancer,” Clinical Chemistry, vol. 40, N90.4, pp. 510-512, (1994).Culver KW. Clinical application of gene therapy for cancer[J].Clinical Chemistry,1994.510-512.Culver, K. W. Clinical application of gene therapy for cancer. ...
Advances in addressing the inherent challenges of gene therapy, particularly related to retaining the delivery efficacy and minimizing unwanted immune responses, provide the basis for the widespread clinical applications of gene medicine. Several types of genes delivered by viral or non锕檌ral delivery ...
Clinical applications of gene therapy for primary immunodeficiencies Hum Gene Ther, 26 (2015), pp. 210-219 CrossrefView in ScopusGoogle Scholar 32 K Boztug, M Schmidt, A Schwarzer, PP Banerjee, IA Díez, RA Dewey, et al. Stem-cell gene therapy for the Wiskott-Aldrich syndrome N Engl J...
405, Gene Therapy & Clinical Therapeutics, Autologous fibroblasts therapy for recessive dystrophic epidermolysis bullosa J Jackow, M Titeux, S Charbonnier and A Hovnanian Inserm UMR 1163 and Imagine Institute of Genetic Diseases, Paris, France Recessive dystrophic epidermolysis bullosa (RDEB) is a sev...
VSTs targeting Epstein–Barr virus (EBV) have the most substantial evidence of efficacy, with few adverse events, leading to the first regulatory approval of VSTs for use in oncology practice. Adoptive cell therapy has not yet achieved success in the treatment of all virus-associated cancers owing...
clinical applications is lacking, especially from a surgical perspective. Tissues that have been damaged, whether by disease or a surgeon’s scalpel, respond by inflammatory and regenerative dynamics,14making surgery a perfect arena for stem cell-derived exosome therapy.15Stem cell-derived exosomes ...
Human Gene Therapy, the flagship, is published 12 times per year. HGT Methods, a bimonthly journal, focuses on the applications of gene therapy to product testing and development. HGT Clinical Development, a quarterly journal, serves as a venue for publishing data relevant to the regulatory ...
- Proteomics - Clinical Applications 被引量: 0发表: 2024年 An experimental model of retrovirus gene therapy for malignant brain tumors Moolten, FL, Fleet, C, Mineta, T, Breakefield, XO, Martuza, RL (1993) An experimental model of retrovirus gene therapy for malignant brain tumors... Y Ta...
Gene therapy has achieved a breakthrough in the treatment of several diseases, especially tumors. In the current review, a discussion is provided on the various strategies that have been developed for HCC gene therapy, the functional and genetic materials used, and their diverse delivery systems, ...
There are two main types of viral vector; adenoviral vectors and lentiviral vectors. Recombinant adenoviral vectors (rAAV) are the most widely used platform for in vivo gene therapy applications due to the excellent clinical safety profile.8 However clinically challenges exist, from the immunogenicity...