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Genetics. The discipline of pharmacogenetics explores differences between individuals in their response to drugs, including study of the polymorphic nature of metabolic enzyme systems. This is more thoroughly described in the human than in companion animals. Breed effects include: – the sensitivi...
The importance of a more therapeutically oriented perspective for pharmacokinetics has been repeatedly advocated and stressed during the past few years. Re
Pharmacogenetics Prenatal diagnosis Dysmorphology The Application of Clinical Geneticsendorses thefor pharmacogenetic studies. Authors are required to upload a completed STROPS checklist (and any applicable secondary checklists specific to the study design – for example theCONSORTchecklist for a randomized c...
Implementation of pharmacogenetics at Cincinnati Children’s Hospital Medical Center: lessons learned over 14 years of personalizing medicine. Clin Pharmacol Ther. 2019;105(1):49-52. doi:10.1002/cpt.1165 PubMedGoogle Scholar 8. Ji Y, Skierka JM, Blommel JH, ...
《国际临床药理学和治疗学杂志》(International Journal Of Clinical Pharmacology And Therapeutics)是一本由Dustri-Verlag Dr. Karl Feistle出版的以医学-药学为研究特色的国际期刊,发表该领域相关的原创研究文章、评论文章和综述文章,及时报道该领域相关理论、实践和应用学科的最新发现,旨在促进该学科领域科学信息的快速...
The application of pharmacogenetics holds great promise for individualized therapy. However, it has little clinical reality at present, despite many claims. The main problem is that the evidence base supporting genetic testing before therapy is weak. The pharmacology of the drugs subject to inherited ...
pharmacogeneticshas been used for this purpose and also to aid in drug selection. Progress in this area has been made possible by the development ofpharmacokineticsas it relates to the absorption, distribution, and elimination of drugs. Central to this effort has been the assessment of renal ...