Director of Phase I and Cancer Genomics Program / BMO Chair in Precision Genomics, Princess Margaret Cancer Centre, Toronto, Canada Learn More Dr. Xiuqin Wang, MD, PhD Director of Research Operating Office, Jiangsu Academy of Clinical and Translational Research ...
This narrative review summarizes what is currently known about how SARS-CoV-2 infects cells and causes disease as a basis for considering whether
Department of Surgery and Cancer, Imperial College London and Imperial College Healthcare NHS Trust, London, United Kingdom (Al-Beidh, Gordon); Intensive Care Unit, Raymond Poincaré Hospital (AP-HP), Paris, France (Annane); Simone Veil School of Medicine, University of Versailles, Versailles,...
Lucia’s research interests are in: translational medicine (particularly on genome and epigenome deregulation in cancer), stemness, differentiation, cell death processes, and the application of epigenome-based drug discovery approaches in human diseases. As a co-Editor-in-Chief, she is committed to...
The liver is controlled by several metabolic hormones, including thyroid hormone, and characteristically displays high lysosomal activity as well as metabolic stress-triggered autophagy, which is stringently regulated by the levels of hormones and metabo
mRNAs encoding the same polypeptide but using different codons can produce dramatically different amounts of protein [206,243]. Synonymous codon changes may affect protein conformation and stability, change sites of post-translational modification, and alter protein function [223]. It is therefore not...
and translational researchers, all of whom were committed to finding novel medicines to treat diseases. The passion and drive of these academic researchers to explore the unknown would be hard to replicate within a pharmaceutical company, which are large, matrixed organizations that are generally risk...
conceived the study and oversaw the manuscript preparation. All authors have read and agreed to the published version of the manuscript. Funding This research was funded by the Clinical and Translational Science Institute at Children’s National (CTSI-CN) through the National Institutes of Health (...
Therefore, we will focus on in-patient rehabilitation and some specific topics that are clinically relevant in neurorehabilitation of TBI, and point out what distinguishes it from the care of patients suffering from other brain injuries. Med. Sci. 2019, 7, 47; doi:10.3390/medsci7030047 www.mdpi...
Despite host antiviral responses and antiretroviral therapy, HIV-1 continues to persist in myeloid cell reservoirs. Hence, strategies that promote the elimination of myeloid reservoirs are critically needed. Insight into host-HIV interactions is key to achieving a cure. ...