Impact factor: 11.5(2023) Published online:2024-01-25 研究背景 胰腺导管腺癌(Pancreatic cancer ,PDAC) 是一种致命的癌症,其中促纤维化hedgehog(HH)信号的旁分泌激活导致间质扩增,从而影响肿瘤药物传递、疗效和患者生存。平滑受体(SMO)抑制剂(sHHi)阻断HH介导的肿瘤间质串扰,可通过短暂增加血管通透性来增加药物递...
Impact factor: 11.5(2023) Published online:2024-01-25 研究背景 胰腺导管腺癌(Pancreatic cancer ,PDAC) 是一种致命的癌症,其中促纤维化hedgehog(HH)信号的旁分泌激活导致间质扩增,从而影响肿瘤药物传递、疗效和患者生存。平滑受体(SMO)抑制剂(sHHi)阻断HH介导的肿瘤间质串扰,可通过短暂增加血管通透性来增加药物递...
November 02, 2023 [MEDLINE Abstract] FAM171B stabilizes vimentin and enhances CCL2-mediated TAM infiltration to promote bladder cancer progression. November 02, 2023 [MEDLINE Abstract] Circulating small extracellular vesicle-derived splicing factor 3b subunit 4 as a non-invasive diagnostic biomarker of...
Chemoresistance: impact of nuclear factor (NF)-kappaB inhibition by small interfering RNA. Commentary re J. Guo et al., Enhanced chemosensitivity to irinotecan by RNA interference-mediated down-regulation of the NF-kappaB p65 subunit. Clin Cancer Res 2004;10:3333-3341. ...
Sharo, A.G., Zou, Y., Adhikari, A.N.et al.ClinVar and HGMD genomic variant classification accuracy has improved over time, as measured by implied disease burden.Genome Med15, 51 (2023). https://doi.org/10.1186/s13073-023-01199-y ...
European Journal of Human Genetics (2023) Prevalence of BRCA1, BRCA2, and PALB2 genomic alterations among 924 Taiwanese breast cancer assays with tumor-only targeted sequencing: extended data analysis from the VGH-TAYLOR study Han-Fang Cheng Yi-Fang Tsai Chi-Cheng Huang Breast Cancer Research...
Impact factor: 11.5(2023) Published online:2024-01-25 研究背景 胰腺导管腺癌(Pancreatic cancer ,PDAC) 是一种致命的癌症,其中促纤维化hedgehog(HH)信号的旁分泌激活导致间质扩增,从而影响肿瘤药物传递、疗效和患者生存。平滑受体(SMO)抑制剂(sHHi)阻断HH介导的肿瘤间质串扰,可通过短暂增加血管通透性来增加药物递...