ICH指导原则Q1f Stability Data Package for Registration in Climatic Zones III and IV英文原版.pdf,INTERNATIONAL CONFERENCE ON HARMONISATION OF TECHNICAL REQUIREMENTS FOR REGISTRATION OF PHARMACEUTICALS FOR HUMAN USE DRAFT CONSENSUS GUIDELINE STABILITY DATA
(<19°C) Meanannualwater Vapourpartialpressure upto15°C upto20.5°C upto11mbar >15–22°C >20.5–24°C >11–18mbar >22°C >24 upto15mbar >22°C >24 >15mbar ICHQ1FC61 CountriesassignedtotheclimaticzonesIIIandIV(4): America:Barbados,Belize,Brazil,CostaRica,DominicanRepublic,Ecuador,...
The figures graphically emphasize the shortage of climatic informa- tion extending back to the Medieval Warm Period for at least 7 geographical zones: the Australian and Indian con- tinents, the SE Asian archipelago, large parts of Eastern Europe/Russia, the Middle Eastern deserts, the tropical ...
The overall observation of individual clustering according to source population affiliation was confirmed by the NJ tree using filtered SilicoDArT markers (Fig.S2). The tendency of geographically close populations to be grouped together was also observed. As reported previously, individuals from the west...
IMIS stations are typically located above 2000 m asl, often close to avalanche starting zones. For most of these stations, the first fully operational year was 2000. In addition to wind and temperature (air and ground), snow depth is measured by an ultrasonic sensor (SR50, Campbell ...
(IMGW-PIB2022; Tomczyk and Szyga-Pluta2019), resulted in shift of agro-climate zones about 500 km to the north during the recent 50 years (Ceglar et al.2019), enabling spring-sown cultivation of crops natively originating from warmer regions, such as soybean, likely domesticated in ...
Bolikhovskaya, N.S., Experience in Typing Pleistocene Periglacial Vegetation in Loess Regions of Glacial and Extraglacial Zones of the Russian Plain, Byull. Komissii po Izucheniyu Chetvertichnogo Perioda, 1998, no. 68, pp. 20–32. Boyarskaya, T.D. and Malaeva, E.M., Razvitie rastite...
The length of the growing season is projected to increase by about 30 to 50 days by the 2080s for the RCP8.5 scenario, and USDA hardiness zones are projected to shift by about one full zone throughout IN. By the 2080s, all GCM simulations for the RCP8.5 scenario show higher annual ...
South Asia is home to one of the fastest-growing populations in Asia, and human activities are leaving indelible marks on the land surface. Yet the likelihood of successive observed droughts in South Asia (SA) and its four subregions (R-1: semi-arid, R-2: arid, R-3: subtropical wet, ...
These three sites have a latitude gradient and belong to different geocryological zones (i.e., sporadic and discontinuous permafrost zones). The main objectives were (1) to characterize the changes in frozen ground based on various data from the 1970s to the 2000s, and (2) to identify ...