Cyclopentadiene is one of the most reactive dienes in normal electron-demand Diels-Alder reactions. The high reactivities and yields of cyclopentadiene cycloadditions make them ideal as click reactions. In this review, we discuss the history of the cyclopentadiene cycloaddition as well as applications ...
1. A process for the preparation of crosslinked derivatives of polycarboxylated polysaccharides, wherein at least one of the polysaccharide chains consists of a derivative of hyaluronic acid, crosslinked by means of “click chemistry”-type reactions, said process comprising the following phases: i) ...
While the classic click Cu(I)-catalysed azide-alkyne cycloadditions have been a benchmark in many areas of recent synthetic chemistry, side reactions and toxicity of the copper catalyst often limit its utilization in biological applications [33], [34]. By replacing terminal alkynes with strain-...
It is demonstrated that ROMP of the mixture of stereoisomers of NBAzl obtained by Diels-Alder reaction between 2-vinyl-4,4-dimethyl-5-oxazolone (vinyl azlactone, VDM) and cyclopentadiene leads to well-defined polymers ( M n , SEC up to 52 500gmol 1 , < 1.37). The resulting polymers ...
Click chemistryPostpolymerization modificationRing-opening metathesis polymerization (ROMP) of a heterofunctional azlactone-based monomer, namely norbornenyl azlactone (NBAzl), is reported for the first time using third generation ruthenium-based catalyst (G3'). It is demonstrated that ROMP of the ...
click chemistry; Diels–Alder reaction; chitosan; PEG-maleimide; furan; rheology 1. Introduction Chitosan is one of the most abundant polysaccharides in nature. It exhibits biological properties such as low toxicity, mucoadhesivity, biocompatibility, and biodegradability, which make it attractive for ...