Molecular Weight(MW) 17 kDa (note) Tissue Specificity Caspase 9 (Cleaved-Asp353) Antibody detects endogenous levels of fragment of activated Caspase 9 resulting from cleavage adjacent to Asp353. Application Application Western blot analysis of extracts from NIH-3T3 cells, treated with Eoside 25uM ...
This Cleaved PARP (Asp214) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 205-225 amino acids from the human region of human Cleaved PARP (Asp214). 反应种属 Human 应用 WB 分子量 Predicted molecular weight: 113kD ...
Calculated Molecular Weight32 kDa Observed Molecular Weight17 kDa, 19 kDa GenBank Accession NumberNM_032991 Gene SymbolCaspase 3 Gene ID (NCBI)836 ConjugateUnconjugated FormLiquid Purification MethodProtein A purfication UNIPROT IDP42574 Storage BufferPBS Only ...
Observed Molecular Weight17 kDa GenBank Accession NumberNM_032991 Gene SymbolCaspase 3 Gene ID (NCBI)836 ConjugateUnconjugated FormLiquid Purification MethodAntigen affinity purification Storage BufferPBS with 0.02% sodium azide and 50% glycerol pH 7.3. ...
Cited in 131 publications. cleaved-Caspase 3 antibody for WB, IP, IF, IHC, ELISA and reacts with human, mouse, rat.
9 GSDMD palmitoylation and cell death in primary BMDMs. a, GSDMD palmitoylation detected by ABE in primary caspase-1/11 dKO BMDMs upon dsDNA electroporation, flatox treatment or LPS electroporation, and treated or not with ROS activator Rot, 2-BP, or ROS quencher NAC. b-g, PI positivity (...
Cross-talk between necrotic (calpain) and apoptotic (caspase) pathways is complex. Calpain cleaves caspase-9 and -3, rendering them inactive. In contrast, calpain has been suggested to cleave and activate caspase-12 (11, 30). We show that calpain is able to cleave Bid to its active form,...
Caspase-1 engages full-length gasdermin D through two distinct interfaces that mediate caspase recruitment and substrate cleavage. Immunity 53, 106–114 (2020). Article CAS PubMed PubMed Central Google Scholar Brigidi, G. S. & Bamji, S. X. Detection of protein palmitoylation in cultured ...
Comparative genomics of sirenians reveals evolution of filaggrin and caspase-14 upon adaptation of the epidermis to aquatic life The mammalian epidermis has evolved to protect the body in a dry environment. Genes of the epidermal differentiation complex (EDC), such as FLG (filaggrin)... J Stein...
Active Caspase-6 (Casp6) and Tau cleaved by Casp6 at amino acids 402 (Tau∆D402) and 421 (Tau∆D421) are present in early Alzheimer disease intraneuronal neurofibrillary tangles, which are made primarily of filamentous Tau aggregates. To assess wheth