Cell–cell communications of various cell populations within tumor microenvironment play an essential role in primary tumor growth, metastasis evolution, and immune escape. Nevertheless, comprehensive investiga
hypomethylated-downregulated (yellow), hypermethylated-downregulated (light green) and hypomethylated-upregulated (green) genes. The percentage of each group in promoter, alternative promoter and gene-body DM CpGs are labeled on the corresponding bar ...
we performed the pull-down assay in 786O cells using the biotin-labeled probe of circPOLR2A. As shown in Supplemental Fig.2a, AGO2, a key protein participating in miRNA sponges, was not determined in the precipitates of the circPOLR2A probe via...