RENAL cell carcinomaBONE metastasisTHERAPEUTICSTREATMENT effectivenessPROGRESSION-free survivalIntroduction: The phase 3 CLEAR study demonstrated that lenvatinib plus pembrolizumab significantly improved efficacy versus sunitinib as first-line treatment for patients with advanced renal cell ...
The molecular features that define clear cell renal cell carcinoma (ccRCC) initiation and progression are being increasingly defined. The TRACERx Renal studies and others that have described the interaction between tumour genomics and remodelling of the tumour microenvironment provide important new insights...
Clear cell renal cell carcinoma (ccRCC) is the most common renal cancer and frequently diagnosed at an advanced stage. It is prone to develop unpredictable metastases even with proper treatment. Antiangiogenic therapy is the most effective medical treatment for metastatic ccRCC. Thus, exploration of...
CA-IX is a good marker to distinguish clear cell renal cell carcinoma with TFE3 strong positive immunostaining from Xp11 translocation renal cell carcinoma. Tumor necrosis could be a potential factor relevant to pT3a stage, which may be a high-risk factor for the patients with Xp11 ...
Renal clear cell carcinoma emerging in a transplanted kidney 3 years after return to dialysis. Case report and review of the literature. Renal clear cell carcinoma emerging in a transplanted kidney 3 years after return to dialysis. Case report and review of the literature... Elazary,Ram,Schlager...
Renal cell carcinoma comprises 2 to 3% of malignancies in adults with the most prevalent subtype being clear-cell RCC (ccRCC). This type of cancer is well characterized at the genomic and transcriptomic level and is a...
Most clear cell renal cell carcinomas are CD10 positive, whereas müllerian-derived clear cell carcinomas are negative.173 Yolk sac tumor and alveolar soft part sarcoma, both rare primary tumors of the cervix, have their own characteristic features, which are presented elsewhere in this chapter. ...
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摘要: Review on Kidney: Clear cell renal cell carcinoma, with data on clinics, and the genes involved.关键词: Chromosome 3 Common renal cell carcinoma (alias Conventional renal cell carcinoma (alias Non papillary renal cell carcinoma (alias Mini Review ...
Genetic changes underlying clear cell renal cell carcinoma (ccRCC) include alterations in genes controlling cellular oxygen sensing (for example, VHL) and the maintenance of chromatin states (for example, PBRM1). We surveyed more than 400 tumours using d