The advent of PD1/PD-L1 inhibitors has significantly transformed the therapeutic landscape for clear cell renal cell carcinoma (ccRCC). This review provides an in-depth analysis of the biological functions and regulatory mechanisms of PD1 and PD-L1 in ccRCC, emphasizing their role in tumor immune ...
Kinases play critical role in clear-cell renal cell carcinoma (ccRCC). We aim to exploit novel kinase that is both protumorigenic and drugable in ccRCC. Reproduction of public datasets with validation using microarray was performed to identify candidate
Kidney cancerMortalitySurvivalDepressionanxietyOBJECTIVES :Anxiety and depression have been associated with inferior overall survival for several malignancies, including metastatic renal cell carcinoma (RCC). However, there is minimal data evaluating this association for localized RCC. We evaluated the ...
Keywords: glycogen;breast cancer;SEER program database;clear cell carcinoma;prognosis;survival
bioengineering Article Effects and Prognostic Values of Circadian Genes CSNK1E/GNA11/KLF9/THRAP3 in Kidney Renal Clear Cell Carcinoma via a Comprehensive Analysis Shujing Li 1,2 , Xianggang Wang 1 , Qingqing Wang 1, Kaixin Ding 1, Xin Chen 1, Yun Zhao 1, Yu Gao 1,3,* and Yuanyuan ...