Cross-linking of FcepsilonRI causes Ca2+ mobilization via a sphingosine kinase pathway in a clathrin-dependent manner. Cell Calcium 45: 99-108.RYU S D,LEE H S,SUK H Y,et al.Cross-linking of Fcepsil-onRI causes Ca2+mobilization via a sphingosine kinase pathwayin a clathrin-dependent manner...
Studies on β-arrestin2 and Mdm2 mutants with modified nucleocytoplasmic shuttling properties have revealed that β-arrestin2 ubiquitination occurs in the nucleus in a Gβγ- and clathrin-dependent manner. The nuclear entry of both β-arrestin2 and Mdm2 commonly relies on the presence of importin ...
Cell Surface Colony-Stimulating Factor 1 Can Be Cleaved by TNF-\\u00a0 Converting Enzyme or Endocytosed in a Clathrin-Dependent Manner 喜欢 0 阅读量: 16 作者:Horiuchi,K.,Miyamoto,T.,Takaishi,H.,Hakozaki,A.,Kosaki,N.DOI: 10.4049/jimmunol.179.10.6715 被引量: 166 ...
Studies on β-arrestin2 and Mdm2 mutants with modified nucleocytoplasmic shuttling properties have revealed that β-arrestin2 ubiquitination occurs in the nucleus in a Gβγ- and clathrin-dependent manner. The nuclear entry of both β-arrestin2 and Mdm2 commonly relies on the presence of importin ...
Here we show in a human cell line model of endocytosis (HEK293 cells) that cholesterol exerts these effects in a dose-dependent and linear manner, over a wide range of concentrations (-40% to +40% variations of plasma membrane cholesterol induced by methyl-beta-cyclodextrin (MBCD) and M...
Numb endocytic adapter proteins regulate the transport and processing of the amyloid precursor protein in an isoform-dependent manner: implications for Alzheimer disease pathogenesis. J Biol Chem 2008; 283: 25492–25502. Article CAS PubMed PubMed Central Google Scholar Schjeide BM, Schnack C, ...
Using a cell culture system enriched for oligodendrocyte progenitor cells, we determined, that oligodendrocyte progenitor cells bind ferritin in a saturable and competitive manner with a Kd of 5 nM and a receptor density of 0.06 fmol bound/20,000 cells. FITC tagged ferritin is internalized by...
This is very similar to FcγRI (CD64), which can undergo endocytosis in the absence of γ-chain in a tyrosine kinase-independent manner [45]. In compari- son, tyrosine kinase is required for the endocytosis of FcγRIIA [46]. These data suggest that endocytosis of dif- ferent Fc ...
Here, 40 different proteins come together on the cytosolic side of the plasma membrane in highly orchestrated manner, to sort and cluster cargo molecules and to recruit adaptor and scaffold proteins to form a clathrin-coated pit. During pit maturation, more and more molecules are recruited and ...
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