Clastogenic activity of 2-chlorodeoxyadenosine in mammalian somatic cellshuman lymphocytes2-CdAchromosomal aberrationsSCEcell cycleThe base analogue 2-chlorodeoxyadenosine (2-CdA) used for therapy in chronic resistant and advanced lymphoproliferative disorders, is cytotoxic for both dividing and non-dividing ...
F. Stich, “Clastogenic activity of caffeic acid and its relationship to hydrogen peroxide generated during autooxidation,” Mut . Res . 116 333–339 (1983).Hanham, A.F., B.P. Dunn and H.F. Stich (1983) Clastogenic activity of caffeic acid and its relationship to hydrogen peroxide ...
The A. vinelandii recA gene was localized on adjacent PstI fragments of 1.3 and 1.7 kb. The cloned A. vinelandii recA gene was functionally analogous to the E. coli recA gene. It was also able to complement the E. coli recA mutation for homologous recombination. A recA deletion mutant of...
Hoffmann. Modulation of the clastogenic activity of ionizing radiation and bleomycin by the aminothiol WR-1065. Environ. Mol. Mutagen. 22: 225-230, 1993.LittlefieldJL.G. and Hoffmann,G.R. (1993) Modulation of the clastogenic activity of ionizing radiation and bleomycin by the aminothiol WR ...
It was performed a QSAR study () that allowed to use a structure clastogenic activity relationship model, which encodes topological information to a substructural level, according to the TOPS-MODE approach (). The predictions were made using the technique of linear discriminant analysis. The used ...
Solubility of low-solubility chromates and their clastogenic activity in cultured cells 来自 Semantic Scholar 喜欢 0 阅读量: 46 作者:K Koshi,K Iwasaki 摘要: Low-solubility chromates, such as lead chromate, zinc chromate and calcium chromate, which were potent carcinogens, were examined for their...
The objective of this study was to investigate the clastogenic activity of plasma ultrafiltrates from HIV-1 infected patients. Clastogenic factors are chromosome-damaging agents with low molecular weight (< 10,000 daltons) which cause chromosome aberrations, sister chromatid exchanges, DNA strand ...
Oxygen radical scavengers inhibit clastogenic activity induced by sonication of human serum. Free Radic Biol Med 1994;16:363-371.Oxygen rad-ical scavengers inhibit clastogenic activity induced bysonication of human serum. Pinamonti S,Chicca MC,Muzzoli M,et al. Free Radical Biology and Medicine . ...
Metronidazole exhibits no clastogenic activity in a double‐blind cross‐over study on Crohn's patients 来自 Semantic Scholar 喜欢 0 阅读量: 27 作者:F Mitelman,BODIL STRMBECK,BO Ursing,RJAN NORDLE,BERYL HARTLEY‐ASP 摘要: Chromosome analysis was carried out on 22 patients with Crohn's disease...
Clastogenic and anticlastogenic activity of glucocorticoid hormones hydrocortisone, prednisolone, and dexamethasone was studied by counting chromosome aberrations in Crepis capillaris test system. Hydrocortisone in a concentration of 12.5 mg/ml produced a clastogenic effect and increased the number of chromosome...