In this respect, PRODISTIN, a computational method permitting the functional classification of proteins based on the analysis of the interaction network is presented along with the main conclusions it allowed us to reach.doi:10.1002/047001153X.g303314Christine Brun...
To understand the structure-to-function relationship, life sciences researchers and biologists need to retrieve similar structures and classify them into the same protein fold. In this paper, we propose a 3D structure-based approach for efficient classification of protein molecules. Classification is ...
PROTEIN FOLD RECOGNITION BASED ON STRUCTURAL CLASSIFICATION基于结构分类的蛋白质折叠模式识别方法蛋白质折叠模式识别结构分类平均势SCOPThreading对用于折叠模式识别的蛋白质结构数据库进行结构分类,构建了四个分类库:Al-α库,Al-β库,α/β库,α+β库和一个总库,然后分别统计出不同灵敏度的匹配评估函数(平均势)....
The COG protein classification scheme is based on orthologous (ortholog: the functional equivalent of a gene/protein function between two genomes) relationships between functionally related proteins from different organisms. From:Encyclopedia of Microbiology (Third Edition),2009 ...
Because a priori knowledge about function of G protein-coupled receptors (GPCRs) can provide useful information to pharmaceutical research, the determination of their function is a quite meaningful topic in protein science. However, with the rapid increase of GPCRs sequences entering into databanks,...
S. et al. Three-dimensional reconstruction of brain-wide wiring networks in Drosophila at single-cell resolution. Curr. Biol. 21, 1–11 (2011). Article CAS PubMed Google Scholar Shih, C. T. et al. Connectomics-based analysis of information flow in the Drosophila brain. Curr. Biol. 25...
In this paper, we proposed a new method that combines PPI information and protein sequence information to boost the prediction performance based on collective classification. Our method divides function prediction into two phases: First, the original PPI network is enriched by adding a number of edge...
Structural insight of the protein–protein interaction (PPI) interface can provide knowledge about the kinetics, thermodynamics and molecular functions of the complex while elucidating its role in diseases and further enabling it as a potential therapeut
structure and functional information to provide a hierarchical classification of knownprotein domainsin thePDB. Fold classification based on Structure-Structure alignment of Proteins (FSSP) (Holm and Sander, 1996) classifies protein structures based on the pair-wise structural comparison ...
Pectin has a complex structure and diverse biological activities, such as immune regulation, anti-tumor, anti-oxidation, hypoglycemic, and improving gastrointestinal function. Some specific sources of pectin can be used as natural multifunctional food additives, used as gelling agents, thickeners, ...