It is not then the study of drugs in a vacuum, as isolated pharmacological effects, which will help us understand drug addiction; rather it is the socialmeaningsascribed to a particular drug in a specific society or culture that we must analyse (Young, 1971: 34). log in via an institution...
Classification of drugs by discriminant analysis using fragment molecular connectivity - Henry, Block - 1979 () Citation Context ... compounds. Descriptors are then derived by comparing the structure of each compound with this template. Such approaches have, for example, been used by Cammarata and ...
One of these drugs, and perhaps the most infamous, was hydroxychloroquine— an antiparasitic drug. This is not uncommon: a myriad of antiparasitic and antibiotic drugs display antiviral activity. Repurposing existing drugs So far, no BST has been established through de no...
An example of how MEs were identified from the case descriptions (n = 58) and categorized with Basger et al.’s aggregated DRP classification system [21] Full size image The identified MEs (n = 100) fell into all nine main categories of Basger et al.'s classification, 21/33...
Many of these drugs have mechanisms of action that are shared with drugs found in multiple classes. For example, amiodarone, a Class III antiarrhythmic, also has sodium and calcium-channel blocking actions. Many of the Class I compounds also affect potassium channels. Some of these drugs could ...
Exclusion criteria for the MNC were presence or history of major internal or neurological disorder, dependence on or recent abuse of alcohol or drugs, hypertension, and general MRI contraindications. BD and FOR2107 have similar exclusion criteria; details are described in Supplementary Table S1 and ...
For example in Fig. 1, when predicting how likely dx interacts with d4, we assign d1, d3, d5 and d7 with positive labels, d2 and d6 with negative labels respectively. Then, we train a classifier C specific to di by the labels L of the drugs and their pairwise similarity matrix...
For example, Campillos et al. proposed an algorithm to predict whether two drugs share target protein based on similarities of phenotypic side-effect [6]. Bleakley et al. developed a supervised method, shown as a bipartite graph, to predict drugs targeting a given protein [7]. The AUC of ...
A stem code can also be qualified by being clustered with one or more “extension codes”, which can only be used in clusters (Table 1). ICD-11-MMS provides over 20,000 extension codes, many of which are of a few types, such as a hierarchical list of drugs and other substances that...
to amendtheclassificationofcertain drugs and to add new drugs to facilitate up-to-date controls. legco.gov.hk legco.gov.hk 修訂規例亦旨在更改若干藥物的分類,同時加入新藥物,以便 施行切合現況的管制。 legco.gov.hk legco.gov.hk [...]