Mayo Clinic, Jacksonville, FL, USA; 2Department of Neurology, Emory University, Atlanta, GA, USAAbstract: Perampanel (2-[2-oxo-1-phenyl-5-pyridin-2-yl-1,2-dihydropyridin-3-yl] benzonitrile hydrate) is the latest in the line of new antiepileptic drugs with a novel mechanism of action. ...
ofactionperampanelreviewPerampanel (2-[2-oxo-1-phenyl-5-pyridin-2-yl-1,2-dihydropyridin-3-yl] benzonitrile hydrate) is the latest in the line of new antiepileptic drugs with a novel mechanism of action. Perampanel inhibits 伪-amino-3-hydroxy-5-methyl-4-isoxazole-propionic ac...
The article presents a list of top 25 drug classes included in step therapy in the United States. The number one drug class included in step therapy is the antiulcer/ulcer combination. This is followed by cholesterol reducers, pain treatment drugs for rheumatoid arthritis/osteoarthritis, antidepress...
Amantadine produced a reproducible inhibition of HHV-6 replication, albeit at relatively high concentrations. Except for lamotrigine, which was moderately active against HHV-6B, several antiepileptic drugs were shown to have no activity. We included several compounds which we previously described as ...
AntiepilepticNeurolepticsBeta-blockersSwitchbackPrimary carePurpose The purpose of this study was to measure the rate of substitution failure to generic antiepileptic drugs (AEDs) compared to two other pharmacotherapeutic classes (neuroleptics, beta-blockers).Molinier, AliciaPalmaro, AuroreRousseau, ...
Valproic acid (VPA) is one of the most effective antiepileptic drugs, and exposing animals to VPA during gestation has been used as a model for autism spectrum disorder (ASD). Numerous studies have shown that impaired synaptic transmissi... YX Yuan,Y Liu,J Zhang,... - 《Translational Psych...