Corticosteroids also known as “steroids” are a class of drugs that are synthetic analogs ofsteroidhormones which are naturally produced by the outer portion of the adrenal glands (two small glands located on top of the kidney) known as the cortex. Corticosteroids are anti-inflammatory medicines ...
Part of the book series: Milestones in Drug Therapy MDT ((MDT)) 128 Accesses Abstract Current antiretroviral therapy guidelines [1] recommend the combination of at least two nucleoside retrotranscriptase inhibitors (NRTI) plus at least one protease inhibitor (PI) and/or at least one nonnucleosid...
The most frequent drug-related adverse events are fatigue (15.8%), nausea (10.5%), and infusion-related reactions (10.5%). Exposure increases proportionally from 0.5 to 8.8 mg/kg. The disease control rate (DCR) is 42.9% with 12 of 28 patients deriving clinical benefit including a partial...
The aim of the study was to assess the long term effect of the antiresorptive agents estrogen and salmon calcitonin, the anabolic drug PTH, and combination... L Mosekilde,CC Danielsen,J Gasser - 《Endocrinology》 被引量: 401发表: 1994年 The anabolic effects of parathyroid hormone on cortical...
Compound dosing did not reveal signs of general toxicity as determined by animal weight, organ weight or haematology. Peanut butter plus test drug (in addition to ad libitum standard rodent chow) did not affect weight gain in the adult mice, in contrast to weight loss in 5?mg/kg prednisone...
Irreversible MAO antagonists may require 2 weeks after discontinuation of drug for normal MAO function to return. Therefore these medications should be tapered and discontinued two weeks before elective surgery. If MAOIs are continued, the patient must be prescribed a diet excl...
(VTD), bortezomib/melphalan/prednisone (VMP), and pomalidomide/dexamethasone (POM-D). Inclusion criteria for each of the arms are as follows: VD and VTD arm (newly diagnosed MM, irrespective of transplant eligibility); VMP arm (newly diagnosed MM, transplant ineligible); and POM-D arm (...
USA 2015 Relapsed Lenalidomide and dexamethasone Patients with MM who have received one to three previous lines of therapy IMiD, immunomodulatory drug; MM, multiple myeloma; PI, proteasome inhibitor; SCT, stem-cell transplantation. a Although thalidomide is approved for first line only, it is an ...
“The worry is that if you stimulate stem cells with a growth factor, which is essentially what romiplostim and eltrombopag are, then you could potentially induce some sort of cancerous transformation. However, when the drug is stopped, the reticulin goes away. There have not been any long-te...
Comparison of four-combination chemotherapy programs in metastatic breast cancer. Comparison of multiple drug therapy with cytoxan, 5-fu and prednisone ver... In 126 postmenopausal women with metastatic breast cancer, four chemotherapeutic combination programs were tested. Patients were stratified and ...