Among these peptides, the two motifs GVEDT and GFGG were highly conserved, while the fragment aa338-346 of Eo-eRF1a/b was variable. In additional, I290 and D293 of Eo-eRF1 were also highly conserved. By the site-directed mutagenesis and pull-down analysis, the amino acid D293 in ...
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After 8–10 days of culture, the cells were washed and incubated for 18 h with RPMI 1640/FCS at 37°C in 5% CO2with one of the Sp17 peptides, HIV control peptide, PHA, or medium only. Peptides were used at 10 μmol and all cultures were carried out in triplicate. Gamma-inte...
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The simplest definition of the middle class is a group of people in a society who are neither rich nor poor. The middle class has always been considered vital to a country's political stability and economic growth. The rich and the poor simply distrust each other too much to let the other...
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公开资料显示,ibrexafungerp属于“first-in-class”三萜类抗真菌剂,已于今年6月在美国获批用于VVC治疗。值得一提的是,翰森制药已经与Scynexis公司签订战略合作协议,获得在大中华区开发和商业化ibrexafungerp的独家权益。 截图来源:CDE官网 Ibrexafungerp(SCY-078)是一种新型葡聚糖合成酶抑制剂,它将葡聚糖合成酶抑制...