Nebbioso A, Manzo F, Miceli M, Conte M, Manente L, Baldi A, De Luca A, Rotili D, Valente S, Mai A, Usiello A, Gronemeyer H, Altucci L. Selective class II HDAC inhibitors impair myogenesis by modulating the stability and activity of HDAC-MEF2 complexes. EMBO Rep 2009;10:776-782...
In this study, we conducted a series of unbiased CRISPR screens, including a surface proteome library screen and an integrin-family-focused library screen. As a result, we identified a requirement for integrin αV (ITGAV) and integrin β5 (ITGB5) in tumor cell maintenance. We also exploited...
To probe the mGlu5 inter-subunit activation mechanism, we used a powerful NEB approach to identify saddle points and the minimum energy path (MEP) between the two states68,69. NEB algorithm does not require the definition of collective variables; instead, it maps the transition pathway within t...
In yet another case,Benson v. City of Lincoln, 343 F.R.D. 595 (D. Neb. 2023), the court drew an even finer distinction. In that case, the employer hired an outside attorney to conduct an investigation of a firefighter’s sex-based discrimination complaints. The attorney investigating ...
them with significant and involved roles in projects from inception to end. To achieve creative success, I have always empowered my team to create 12-month objectives rather than chase long-term goals. These short strides build competencies to deliver on promised performance and inspire future ...
Counting in at around 12,000 words, can there be a more influential book with so relatively few words, than the Communist Manifesto? Today (21st February, 2018) is said to be the 170th anniversary of its publication. Written in a six-week rush, after the Communist League imposed a dead...
WANTED: Uncomplaining Plods Prepared to Fly 12,000 Miles Cattle Class Then Live on a Shoestring While Keeping an Eye on a Boozy, Girl-Crazy Young Prince with Form for Lighting Sneaky Spliffs; COPS SNUB PLEA TO BE HARRY'S MINDERS IN OZ Read preview Newspaper article Sunday Mirror (...
2006;12(1):52-9.Popowich K. Comparison of Class I and Class II Treatment Duration Among Three Different Orthodontic Practices. Seminars of Orthodontics 2006;12:52-59.Popowich K, Flores-Mir C, Nebbe B, Heo G, Major PW (2006) Comparison of Class I and Class II treatment duration among ...
. Hence, loss of the native structure by the phosphomimetic mutation does not result in domain disorder but rather in the transition of C-Cdc37 to a conformationally heterogeneous, partially unfolded state. This effect is not an artefact caused by domain truncation. Comparison of the13C-HMQC or...
them with significant and involved roles in projects from inception to end. To achieve creative success, I have always empowered my team to create 12-month objectives rather than chase long-term goals. These short strides build competencies to deliver on promised performance and inspire future ...