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4Department of Medicinal Chemistry, Danish University of Pharmaceutical Sciences, Universitetsparken 2, DK-2100 Copenhagen, Denmark and 5Bioinformatics center, Institute of Molecular Biology and Physiology, University of Copenhagen, Universitetsparken 15, Building 10, 2100 Copenhagen, Denmark Email: Pavel...
A solution of the corresponding crude carbamate precursor 8a–f or 14a–b (ca. 1 mmol) in CH2Cl2 (20 mL) had 4 M HCl in 1,4-dioxane (10 mL) added to it; the solution was left stirring at room temperature for 16 h. Once the reaction was completed, the mixture was extracted with...
Adibehalsadat Ghazanfari 1, Soyeon Kim 3, Kwon Seok Chae 4, Yongmin Chang 3,* and Gang Ho Lee 1,* 1 Department of Chemistry, Department of Nanoscience and Nanotechnology (DNN), College of Natural Sciences, Kyungpook National University (KNU), Taegu 41566, Korea; 20100819@hanmail.net (H....
They are also of great interest in the field of medicinal chemistry as novel anticancer therapeutic agents due to their peculiar reactivity and mechanisms of action with respect to hitherto used drugs. Some derivatives of the pyrazolo[4,3-e][1,2,4]triazine ring system were evaluated against ...