Introduction: Human Mpox (formerly monkeypox) infection is an emerging zoonotic disease caused by the Mpox virus (MPXV). We describe the complete genome annotation, phylogeny, and mutational profile of a novel, sustained Clade I Mpox outbreak in the city of Kamituga in Eastern...
The newly introduced Novaplex™ MPXV/OPXV plus Assay (RUO) is designed to detect 3 targets causing mpox disease: non-variola Orthopoxvirus (OPXV) and monkeypox virus (MPXV) with specific confirmation of MPXV Clade I. MPXV Clade I is associated with higher...
While human mpox resembles smallpox in clinical presentation, there are considerable knowledge gaps regarding conserved molecular pathogenesis between these 2 orthopoxviruses. Thus, we sought to compare MPXV and VARV infections in human monocytes through kinome analysis. We performed a longitudinal ...
reporting rash symptoms and viral presence in blood, kidney, and testicular tissues [Citation23]. However, this study did not provide detailed data on tissue pathology caused by MPXV. Moreover, there is no published research exploring rabbit models in relation to the current ...
Epidemiological and clinical features of mpox during the clade Ib outbreak in South Kivu, Democratic Republic of the Congo: a prospective cohort studyClade Ib, a new strain of clade I monkeypox virus, emerged in eastern DR Congo, sparking an international outbreak. Comprehensive studies are ...
We present interim results of a prospective cohort study of 95 mpox patients assessed 3–20 weeks post-symptom onset. Two-thirds of participants had residual morbidity, including 25 with persistent anorectal and 18 with genital symptoms. Loss of physical fitness, new-onset/worsened fatigue and ...