In this study, 1,741 people with CKD stage 3 wereindividually recruited from 32 primary care practices in Derbyshire, UnitedKingdom. Study visits were undertaken at baseline, year 1, and year 5. Binomiallogistic regression and Cox proportional hazards models were used to modelprogression, CKD rem...
Recently, a new estimator based on creatinine, the CKD-EPI equation, has been proposed which is presumed to better perform in normal GFR ranges. The aim of the study was to measure the difference in prevalence of stage 3 CKD in a population using either the MDRD or the CKD-EPI study ...
The Odds Ratio for uAOG and CKD stage 3 development was significant after adjusting for eGFR, HbA1c, and systolic blood pressure 1.82 (1.00-3.29) but no longer significant when Albumin Excretion Ratio (AER) was included 1.21 (0.65-2.24).In the PRD analysis, uAOG/creatinine was sixfold ...
The eGFR-C study: accuracy of glomerular filtration rate (GFR) estimation using creatinine and cystatin C and albuminuria for monitoring disease progression in patients with stage 3 chronic kidney disease-prospective longitudinal study in a multiethnic population BMC Nephrol, 15 (1) (2014), p. 13...
post hoc analysis of multicenter, randomized, double-blind, placebo-controlled trial data for 395 patients with stage 3 CKD and asymptomatic hyperuricemia. Participants were divided into febuxostat or placebo groups and subcohorts stratified and cross-classified by proteinuria and serum creatinine ...
We performed post hoc analysis of multicenter, randomized, double-blind, placebo-controlled trial data for 395 patients with stage 3 CKD and asymptomatic hyperuricemia. Participants were divided into febuxostat or placebo groups and subcohorts stratified and cross-classified by proteinuria and serum ...
虽然最初认为IgA肾病的病程为良性,但目前发现多达50%的受累患者往往会在20-25年的观察期里缓慢进展为终末期肾病(end-stage renal disease, ESRD)[7]。其余患者进入持续的临床缓解期,或出现持续性低度血尿和/或蛋白尿。虽然可能难以预测一些患者的预后情况,但现已确定了肾病进展的重要危险因素。(参见下文‘疾病进展...
①★肌酐(Creatinine,Crea) 肌酐是肌肉在体内代谢的产物,主要由肾小球过滤排出体外。人类每20g肌肉代谢可产生1mg肌酐。在肉类食物摄入量稳定时,身体的肌肉代谢若无特别大的变化,肌酐的生成量则相对恒定[1]。 注意,对于老年猫和肾病猫,肌酐都不是很好的诊断指标: ...
Congestive heart failure, coronary artery disease, stroke or peripheral vascular disease frequency was lower than 10% The prevalence of eGFR < 60 ml/min x 1.73 m(2) was: stage 3 (30-59 ml/min/1.73 m(2)) 19.7%; stage 4 (15-29 ml/min/1.73 m(2)) 1.2%; stage 5 no dialysis (...
ltration rate (GFR) less than 60 mL/min/1.73 m2 for 3 or more months. Traditionally, CKD is categorized into 5 stages that are based on disease severity de?ned by GFR (3) (Table 1); stages 1 to 3 are considered to be early-stage CKD. People with early stages of the disease are...