另一方面,有研究表明CKD-EPI公式会高估年轻人的eGFRcr[12 ],甚至当青少年成长为成年人连续用CKD-EPI公式计算时,即使血清肌酐(serum creatinine,Scr)结果不变也会得到不同的eGFRcr的结果。为了解决这些挑战,全年龄谱(full age spectrum,FA...
NKF-ASN工作组在2009年和2012年CKD-EPI公式的开发数据集上进行了重新拟合,于2021年在《新英格兰医学杂志》上发布了最新的没有种族eGFR公式,即CKD-EPI 2021方程6,如图1:图1 CKD-EPI 2021方程在横断面研究中7,研究人员使用来自美国国家健...
研究发现用CKD-EPI方程估算GFR能更有效的关注重要因素,从而改善对患者未来风险和肾病治疗的评估。 美国有超过92%的实验室在使用1999年提出的MDRD研究方程计算GFR。这项检测每年实施超过3亿,通过病人的年龄、性别、种族和血清中肌酐serum creatinine水平来计算GFR,是一种衡量血液中产生的分子垃圾的方法。CKD-EPI方程也与...
Performance of the European Kidney Function Consortium (EKFC) creatinine-based equation in United States cohorts [0.51; 0.94] mL/min/1.73m2) was closer to zero than that for the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI2021) equation (1.22, [... P Delanaye,AD Rule,E Schaeff...
1.ThomasStehlé, Yaniss Ouamri, Antoine Morel, et al. Development and validation of anew equation based on plasma creatinine and muscle mass assessed by CT-scan toestimate glomerular filtration rate: a cross-sectional study. Clinical KidneyJournal. Jan 20, 2023.sfad012. ...
In 2021, a new Chronic Kidney Disease Epidemiology (CKD-EPI) Collaboration equation was introduced that excluded race correction. We set out to compare estimated glomerular filtration rate (eGFR) determined using the creatinine-based CKD-EPI 2009 and 2021 equations and the reclassif...
② Multivariate regression logistic analysis indicated that age,systolic blood pressure,cystatin and creatinine were the risk factors for heart failure patients combining with renal insufficiency.Conclusion:For in-hospital patients of chronic heart failure,the elder age,higher systolic blood pressure wi...
Calculate eGFR using CKD EPI 2021 Formula Questions 1.Gender? 2.Age? 3.Creatinine?About The original CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration) equation was developed in 2009 in an effort to create a more precise formula to estimate glomerular filtrate rate (eGFR) from serum...
(CKD-EPI)equation.ThisequationispreferabletotheMDRD(ModificationofDietinRenalDisease)studyequation,becauseitismoreaccurateinhigherrangesofeGFR(>60mL/min/1.73m2)andallowsreportingeGFRcrasanumericvaluethroughouttheentirerange.OtherguidelinesandcommentariesconcurredwiththerecommendationtousetheCKD-EPI2009creatinineequation...
In the RENAAL study, patients with type 2 diabetes and CKD randomized to losartan treatment had a 16% lower risk of developing a doubling of serum creatinine, KFRT, or death compared with the placebo group. Similarly, IDNT reported that irbesartan treatment was associated with a lower risk ...