这 3 点要牢记 正常情况下,肾脏是排泄磷酸盐的主要器官,当肾功能受损时,如慢性肾脏病 (chronic kidney disease, CKD) 早期,肾小球滤过率(GFR)的下降会导致磷酸盐的排泄减少,血液中的磷酸盐(血磷)水平可能会升高超过正常范围。一般认为成人血磷水平高于 4.5～5.5 mg/dL(1.45～1.78 mmol/L)即为高磷血症。 01 ...
这 3 点要牢记 正常情况下,肾脏是排泄磷酸盐的主要器官,当肾功能受损时,如慢性肾脏病 (chronic kidney disease, CKD) 早期,肾小球滤过率(GFR)的下降会导致磷酸盐的排泄减少,血液中的磷酸盐(血磷)水平可能会升高超过正常范围。一般认为成人血磷水平高于 4.5～5.5 mg/dL(1.45～1.78 mmol/L)即为高磷血症。 01 ...
CKD classifica- tion based on estimated GFR over three years and subsequent cardiac and mortality outcomes: a cohort study. BMC Nephrol 2009; 10: 26Weiner DE, Krassilnikova M, Tighiouart H et al. CKD classifica- tion based on estimated GFR over three years and subsequent car- diac and ...
1.Thomas Stehlé, Yaniss Ouamri, Antoine Morel, et al. Development and validation of a new equation based on plasma creatinine and muscle mass assessed by CT-scan to estimate glomerular filtration rate: a cross-sectional study. Cli...
CKD 的定义是肾损害或肾小球滤过率 (GFR) 下降至少 3 个月低于 60 mL/min/1.73 m²。 CKD 根据 GFR 分类如下: 第1 阶段:肾损伤,GFR 正常或升高(>90 mL/min/1.73 m²) 第2 阶段:GFR 轻度降低(60-89 毫升/分钟/1.73 平方米) 阶段3a:GFR 适度降低(45-59 毫升/分钟/1.73 平方米) ...
CKDinform A PCP's Guide to CKD Detection and Dela
Stage 5: Kidney failure (GFR < 15 mL/min/1.73 m2 or dialysis) KDIGO guidelines recommend using creatinine-based formulas for determining the estimated glomerular filtration rate (eGFR) in adults at risk for CKD. If cystatin C is available, the GFR category should be estimated from the combin...
The progressive decline in kidney function is the hallmark of Chronic Kidney Disease (CKD). Kidney damage prevents the kidneys from adequately filtering blood. There are five phases of kidney disease based on th...
第一个证明RAS抑制在非糖尿病性CKD中获益的RCT研究于1997年由GISEN研究小组发表,即雷米普利在非糖尿病性肾衰竭中的应用(REIN)(7)。结果表明对于蛋白尿≥3g/24h的慢性非糖尿病肾病患者,雷米普利治疗减慢GFR下降,显著下降血清肌酐浓度翻倍或ESRD的风险,且以上保护作用与血压降低无关。
73m2andanGFR<60ml/min/1.73m2ispathologicalacrossalladultages,gendersandancestralgroupsIgnoresage-andgender-relatedchangesinGFRLinkedtoanimprecisemeasurementofGFR-the4variableeGFR(MDRD)Allowsthe“diagnosis”ofCKDbasedoneGFRaloneConflatesisolated“microalbuminuria”(inabsencefodiabetesorcorroborating...