肌酸激酶(CK)的共价抑制剂以及其用于治疗和预防癌症的用途.pdf,本公开涉及能够抑制肌酸激酶的式I化合物。本公开还涉及治疗如血液恶性肿瘤等癌症的方法。(19)国家知识产权局 (12)发明专利申请 (10)申请公布号 CN 116323571 A (43)申请公布日 2023.06.23 (21)申请号 2021800
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PDF (213 K) Signal transduction by stress-activated map kinases: Roger J. Davis, Howard Hughes Medical Institute, Program in Molecular Medicine, Department of Biochemistry & Molecular Biology, 373 Plantation Street, Worcester, MA 01605 undefined more undefined Signal transduction by stress-activated ma...
The SPR technique has been widely used for sensing in the physical, chemical, and biological applications, as follow: (i) molecular biology; (ii) clinical search; (iii) biospecific interactions (like antigen-antibody); (iv) enzymatic kinetic; (v) study of the interaction between materials; (...
2 Department of Integrative Biology, University of California, Berkeley, California 94720, USA. Correspondence and requests for materials should be addressed to O.H. (email: ohallats@berkeley.edu). NATURE COMMUNICATIONS | 7:12760 | DOI: 10.1038/ncomms12760 | www.nature.com/naturecommunications 1...
In biology, auxin is a hormone found in plants that promotes growth. Auxin flux canalization = process by which veins become thicker as they grow longer. The longer a vein gets, the more auxin flows through it ("flux"), causing veins to progressively thicken from their tips to their roots...
Key issue in HSC biology has focused on how their commitment to a particular lineage and maturation is regulated at the cellular and molecular levels. Because HSC have been widely used in the treatment of leukemia (Miyamoto et al., 2000) and are present in high frequency in umbilical cord ...
International Journal of Biochemistry and Cell Biology 37(6): 1296-1307 2005ISSN/ISBN: 1357-2725 PMID: 15778092 DOI: 10.1016/j.biocel.2005.01.004Accession: 011685168Full-Text Article emailed within 0-6 h Buy Now for $19.90 Payments are secure & encryptedAbstract...
in Arabnia HR, Valafar H (eds) Proceedings of the 2006 international conference on bioinformatics & computational biology. CSREA Press: Las Vegas, USA, pp 141–146. Heyer J, Galchenko VF, Dunfield PF. (2002). Molecular phylogeny of type II methane-oxidizing bacteria isolated from various ...
1., 12. Thus, the combined use of a maximally-tolerated statin and non-statin cholesterol lowering therapy represents an opportunity for ASCVD risk reduction in PLHIV. Evolocumab, a fully human monoclonal antibody that binds proprotein convertase subtilisin/kexin type 9 (PCSK9), diminishes LDL-...