Description: CJC-1295 CJC 1295 stimulates growth hormone release via binding to the pituitary. This peptide directly mimics the endogenous Growth Hormone Releasing Hormone (GHRH) typically secreted by the hypothalamus. CJC 1295 comes in 2 chemical forms. One includes a binding group called DAC, or...
Compared to the native protein sequence, CJC-1295 has four amino acid substitutions which improve protease resistance, and an additional lysine residue at the C-terminus that incorporates a maleimidopropionic acid group. This maleimidopropionic acid sometimes called the drug affinity complex (DAC), for...
(DAC) moiety and has a shorter half-life than the DAC-conjugated version in the blood.2 CJC-1295 increases the secretion of growth hormone in primary rat anterior pituitary cells when used from picomolar to micromolar concentrations and into rat blood when administered subcutaneously at a dose ...
(DAC) moiety and has a shorter half-life than the DAC-conjugated version in the blood.2CJC-1295 increases the secretion of growth hormone in primary rat anterior pituitary cells when used from picomolar to micromolar concentrations and into rat blood when administered subcutaneously at a dose of...
it has been debated which CJC 1295 is best to use. While MOD GRF (CJC 1295 no DAC) is commonly used with GHRP’s to increase pituitary GH pulse, more frequent injections will need to be administered. The CJC 1295 with DAC will result in a series of smaller pulses; therefore, injections...