(2009) Mapping cis- and trans- chromatin interaction networks using chromosome conformation capture (3C). Methods Mol Biol 464, 105–121.Miele A, Dekker J (2009) Mapping cis- and trans-chromatin interaction networks using chromosome conform...
基因组de novo测序即从头测序,指不需要任何参考基因序列信息即可对某个物种进行测序 chromosome interaction mapping:分析染色体三维组织,以了解染色体的相互作用,因为同一个染色体上的作用为顺式作用;不同染色体之间的作用为反式作用,所以以此明确顺式和反式机制)。 cis- and trans-regulation:顺式和反式作用:相对同一...
A nitrocellulose filter binding assay has been used to assess the interaction of cis- and trans-diamminedichloroplatinum(II) with calf thymus DNA. Local regions of denaturation resulted from cis-DDP interaction and these were attributed to the concerted effect of close platinations in DNA. Single...
Cisandtranseffects can be distinguished by the differences in binding affinities among F0 parents and their F1 offspring, ascis-acting variation must remain allele-specific28,29,32,33,35(Supplementary Figs.4a,5). TFBS that had informative SNVs for allelic resolution were classified into four regula...
A correct understanding of gene expression regulatory mechanisms in the brain is essential to understanding the relationship between genotype and phenotype. Bothcis-acting andtrans-acting factors have the potential to regulate gene expression patterns in the brain and to mediate the interaction between en...
Further mutational studies of the E-cadherin ectodomain fused with the pentamerization domain of cartilage oligomeric matrix protein (E-CADCOMP) seem to indicate that Trp2 docks into an intramolecular hydrophobic pocket, and this process appears to be critical for the trans-interaction event (16, ...
A compensating cis–trans interaction was implied if cis and trans effects of one gene were in the opposite directions [{B > 0 and (A − B) > 0} or {B < 0 and (A − B) > 0}]. In contrast, if cis and trans effects of one gene acted...
molecule will have a slight negative charge while the other side will have a slight positive charge. Therefore, the molecule becomes a polar and dipole-dipole interaction may occur between molecules. These extra intermolecular forces in cis isomer give it a higher boiling point compared to trans ...
(iii) Draw the structures of the cis and trans stereoisomers of compound C.cis trans2](c) The C = C group in an alkene contains a t-bond.Complete the diagram below to show how p-orbitals are involved in the formation of a t-bond.I ..… !一(d)Compound D , shown below, react...
The interaction of calf thymus DNA with cis-DDP, trans-DDP and TDP was studied by 23Na NMR in aqueous solutions at pH = 7.0, with Pt(II) compounds/DNA(P) (P=Phosphate) molar ratios r increasing from 0 till to IP.doi:10.1080/07391102.1998.10508223GeorgesMallet...