Each time your liver gets hurt, it repairs itself and forms tough scar tissue. When too much scar tissue builds up, the organ can't work the way it should. Your doctor might call this condition cirrhosis of the liver. “The liver is essentially the factory of the body, so it is centr...
Emily D. Bethea MD, Sanjiv Chopra MBBS, MACP, in Handbook of Liver Disease (Fourth Edition), 2018 Cirrhosis Definition 1. The word cirrhosis is derived from the Greek word kirrhos, meaning “orange or tawny,” and osis, meaning “condition.” 2. The World Health Organization (WHO) defini...
Cirrhosis is the end complication of manyliverdiseases and is characterized by abnormal structure and function of the liver. The diseases that lead to cirrhosis do so because they injure and kill liver cells. The subsequent inflammation and repair that is associated with the dying liver cells cause...
Up to 50–70% of patients with liver cirrhosis develop hepatic encephalopathy (HE), which is closely related to gut microbiota dysbiosis, with an unclear mechanism. Here, by constructing gut–brain modules to assess bacterial neurotoxins from metagenomic
This study aimed to assess the global, regional, and national burden of liver cirrhosis and other chronic liver diseases between 1990 and 2019, considering five etiologies (hepatitis B, hepatitis C, alcohol use, NAFLD and other causes), age, gender, and
This article is about alcoholic cirrhosis of the liver. Cirrhosis can be caused by other physiological problems and diseases, but alcoholic liver cirrhosis is a social issue that affects not only the person suffering, but also their family and ...
Liver Diseases Anahat Dhillon MD, Randolph H. Steadman MD, in Anesthesia and Uncommon Diseases (Sixth Edition), 2012 Biliary Cirrhosis Biliary cirrhosis is simply cirrhosis caused by biliary obstruction of any type, regardless of location in the biliary tree. Primary biliary disease is defined as ...
Primary biliary cirrhosis (PBC) is an immune-mediated chronic cholestatic liver disease with a slowly progressive course. Without treatment, most patients eventually develop fibrosis and cirrhosis of the liver and may need liver transplantation in the late stage of disease. PBC primarily affects women...
the discovery cohort and identified 12 loci to be associated with cirrhosis in multitrait GWAS with plasma alanine aminotransferase (ALT), a biochemical marker of liver cell injury4. However, the number of sequence variants linked to cirrhosis is low when compared to the hundreds of risk loci ...
the effect of hepatic cirrhosis on the cerebral cortex and subcortical pathways using mfVEP and to elucidate the possibility of using multifocal visual evoked potentials (mfVEPs) for early detection of MHE among patients with compensated liver cirrhosis compared to the validated psychometric testing ...