Panitumumab was administered at a dosage of 6 mg/kg every 2 weeks for 17 months;the treatment was well tolerated, despite the cirrhosis, and the main toxicity was the skin rash. Conclusion: In patients with severe comorbidities such as cirrhosis of the liver and K-ras wild-type carcinomas,...
They found no significant changes in liver biochemistries, Mayo risk score, degree of inflammation, fibrosis nor histologic changes in the treated patients at end of 1 year but found adverse events (gastrointestinal symptoms and skin rash) in 83% (which disappeared shortly after stopping PFD) of...
The main clinical manifestations include lymphadenopathy, night sweats, fever, hepatosplenomegaly, hypergammaglobulinemia, and skin involvement[5]. In this case, another prominent manifestation was the rash and pruritus, with about 44% of AITL patients having truncal papuloplaques, which can also ...
A 43-year-old woman, with a family history of unexplained skin pigmentation, presented with rash after sun exposure since childhood and splenomegaly for 13 years. She also had abnormal liver function over the past few years. She had 3.5 kg weight loss within 2 months. On examination, there ...
Salvia Miltiorrhizae Radix, the 8th herbal medicine used for the present invention, is used for menstrual disorder, menstrual pain and postpartum abdominal pain of women, deep abdominal pain caused by extravasated blood, bruise, insomnia, skin rash and the like. Polyporus, the 9th herbal medicine...
Once the more common infective pustular rashes have been excluded, the differential diagnoses for a pustular skin rash are acute generalized exanthematous pustulosis (AGEP), Sweet's Syndrome (SS), pyoderma gangrenosum (PG) and pustular vasculitis(PV). We present a case of pustular vasculitis ...
SkinFemaleA case is described of primary biliary cirrhosis in a 59 year old woman who initially presented with a rash over her lower legs 18 months before diagnosis. Skin biopsy examination showed non-caseating granulomas of the sarcoid type. It is believed that this is the first reported ...
Extrahepatic graft-versus-host disease (GVHD) was absent. Skin biopsy was equivocal 2 months after transplant, rash was absent during the period of cholestasis, and cholangiographic abnormalities were absent. Liver biopsy 7.5 months posttransplant revealed chronic hepatic GVHD...doi...
biliarycirrhosispruritusThe article presents a case study of a 75-year old man who was brought to the clinic due to complaints of itching and chronic skin rash for about a year. Examinations reveal that the patient has primary biliary cirrhosis (PBC) with pruritus through use of liver biopsy ...
鈥 A 50-year-old woman suffered from a diffuse skin rash, high fever and jaundice immediately after a second injection of glutathion and Stronger Neo-minophagen C which contains glycyrrhizin. Liver biopsy performed 11 months after the onset showed mild spotty hepatocyte necrosis, marked cholestasis...