Portal hypertensive gastropathy, enteropathy, and/or colopathy 3. Hematologic a. Anemia ▪ Folate deficiency ▪ Spur cell anemia (hemolytic anemia in the setting of severe alcoholic liver disease) ▪ Splenomegaly with resulting pancytopenia b. Thrombocytopenia c. Leukopenia d. Impaired coagulation ...
Increased hepatic iron concentration was significantly associated with more severe liver disease ( P < .001), male sex ( P = .05), the presence of spur cell anemia ( P < .0001), and hepatocellular liver disease ( P < .0001). The HFE mutations were uncommon in patients with increased ...
A decrease in red blood cell count suggests cirrhosis-related anemia, which may be caused by splenomegaly, chronic inflammation, and malnutrition37,40,41. Anemia results in reduced tissue oxygenation, further aggravating renal ischemia and impairing kidney function. It also triggers sympathetic over...
To evaluate the predictive performance of the nomogram model, we first calculated the area under the ROC curve (AUC) on the training set and validation set. The nomogram’s AUC was 0.832 (95% CI 0.8069–0.8563) in the training group and 0.8415 (95% CI 0.8042–0.8789) in the validation s...
Pernicious anemia 6 (4) All conditions 84 (53) Adapted from Watt et al. [3]. Pathologically, PBC is characterised by a progressive lymphocytic cholangitis centered on smaller intrahepatic bile ducts, often associated with the presence of granulomata in the liver. Autoantibodies against the componen...