Swaby RF, Cristofanilli M (2011) Circulating tumor cells in breast cancer: a tool whose time has come of age . BMC Med 9 : 43. [ PMC free article ] [ PubMed ]Swaby, R.F.; Cristofanilli, M. Circulating tumor cells in breast cancer: A tool whose time has come of age. BMC ...
might be the most aggressive. Recently, it was demonstrated in vivo that tumor cells proceed through various hybrid epithelial/mesenchymal states with differing invasive, metastatic, and differentiation characteristics [57]. Carcinoma cells residing in intermediate epithelial-mesenchymal...
Circulating Tumor Cells in Breast Cancer Metastatic Disease (Advances in Experimental Medicine and Biology, 1220) This book is aimed to summarise the key aspects of the role of circulating tumour cells (CTCs) in breast cancer, with special attention to their contribution to tumour progression and ...
Yields of tumor cells separated from peripheral blood are low in metastatic breast cancer but are still sufficient for further analysis; in early stages of breast cancer, however, these counts are even lower and frequently do not exceed five CTCs per 7.5 to 10 ml of blood [2]. Identification...
RNA-SeqofCirculatingTumorCellsinStageII–IIIBreast Cancer JulieE.Lang,MD 1 ,AlexanderRing,MD,PhD 2 ,TaniaPorras,MS 1 ,PushpinderKaur,PhD 1 ,VictoriaA.Forte, MD 3 ,NealMineyev,MD 1 ,DebuTripathy,MD 4 ,MichaelF.Press,MD,PhD 5 ,andDanielCampo,PhD ...
This article is in the 69th percentile (ranked 43,448th) of the 153,810 tracked articles of a similar age in all journals and the 66th percentile (ranked 14th) of the 48 tracked articles of a similar age in Breast Cancer Research View more on Altmetric Altmetric calculates a score base...
Circulating tumor cells (CTCs) have tremendous utility in cancer research, aiding researchers in deciphering the complex processes leading to cancer metastasis and in developing more effective cancer therapeutics. Besides the research applications, the detection and analysis of CTCs has enormou...
Circulating tumor cells in breast cancer: Advanced tools for \"tailored\" therapy? Resonance structures arising in two-dimensional maps induced by dynamical systems with 3/2 and 2 degrees of freedom are considered. The basics of resonance theory are stated. Possible structures of degenerate resonance...
We find, using mouse models, that CTC clusters are derived from oligoclonal clumps of primary tumor cells and constitute a rare but very highly metastasis-competent subset of CTCs, compared with single circulating breast cancer cells. RNA sequencing of human breast CTC clusters identifies plakoglobin...
cells that move together in a cancer patient's bloodstream and have strong cell–cell contacts. These cells shed directly from the primary tumor "self-seeding" (1), or they can be formed when single CTCs in the circulation aggregate together and form clusters of tumor cells in other tissues...