et al. Circulating myeloid-derived suppressor cells predict differentiated thyroid cancer diagnosis and extent. Thyroid 26, 381-389 (2016).Angell TE, Lechner MG, Smith AM, Martin SE, Groshen SG, Maceri DR, et al. Circulating myeloid-derived suppressor cells predict differentiated thy- r...
Myeloid-derived suppressor cells (MDSCs) are heterogeneous cell types that suppress T-cell responses in cancer patients and animal models, some MDSC subpopulations are increased in patients with pancreatic cancer. The present study was to investigate a specific subset of MDSCs in patients with pancre...
Myeloid derived suppressor cells (MDSCs) play key roles in cancer development. Accumulation of peripheral-blood MDSCs (PB-MDSCs) corresponds to the progression of various cancers, but provides only a crude indicator. We aimed toward identifying changes in the transcriptional profile of PB-MDSCs ...
In this study, a set of immune biomarkers (myeloid derived suppressor cells, regulatory T cells, and OX40 + and PD-1 + T lymphocytes counts) in peripheral blood of patients diagnosed with advanced breast cancer were analyzed along of first line antineoplastic therapy. Subsequently, a ...
Renal transplant recipients have elevated frequencies of circulating myeloid-derived suppressor cells Renal transplant recipients have elevated frequencies of circulating myeloid- derived suppressor cells. Nephrol Dial Transplant 2012; 27: 402... BD Hock,KA Mackenzie,NB Cross,... - 《Nephrol Dial Transpl...
The TME includes immune cells, such as myeloid-derived suppressor cells (MDSCs), regulatory T cells (Tregs), tumor-associated macrophages (TAMs), dendritic cells, and B cells, as well as nonimmune cells and ECM, which play an important role in tumor recurrence and metastasis [97]. The ECM...
Tumor escape mechanism governed by myeloid-derived suppressor cells. Cancer Res, 68 (2008), pp. 2561-2563 Google Scholar 29 B Zhu, Y Bando, S Xiao, et al. CD11b+Ly-6C(hi) suppressive monocytes in experimental autoimmune encephalomyelitis. J Immunol, 179 (2007), pp. 5228-5237 Google Scho...
We studied circulating myeloid-derived suppressor cells (MDSC) in ipilimumab-treated patients to detect alterations in the myeloid cell compartment and possible correlations with clinical outcome. Lin(-) CD14(+) HLA-DR(-) monocytic MDSC were enriched in peripheral blood of melanoma patients compared...
Accumulating evidences demonstrate that a population of suppressive cells known as myeloid-derived suppressor cells (MDSCs) is key immune modulators which suppress antitumor immunity. In this study, we found that the level of circulating CD14+HLA-DR−/low cells in patients was significantly higher...
myeloid-derived suppressor cells (MDSCs), or cancer-associated fibroblasts (CAFs) to escape the immune system and promote their survival123,124. Recently, accumulating studies suggest that the interaction and modulation between CTCs and hostile blood microenvironment is essential for adhesion to endotheli...